Results 221 to 230 of about 89,325 (290)

"Algal-dromes": a novel conceptual approach to illness in humans exposed to harmful algal bloom toxins. [PDF]

Front Toxicol
Johnson B, Richlen M, Lai J, Twiner MJ.
europepmc   +1 more source

Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity

Advanced Science, Volume 13, Issue 53, 24 September 2026.
Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten, Karen Beets, Tessa Schalley, Janne Verreycken, Gayel Duran, Daphne Lintsen, Lisa Schuetz, Xue Zhong, Rinke Nieuwschepen, Melissa Schepers, Brecht Moonen, Jeroen Bogie, Jana Van Broeckhoven, Carlo Heirman, Jurgen Van den Heuvel, Bart Vanderborght, Ismael Varela, Roxanne Nouille, Lotte Jacobs, Jessica Filtjens, Sabah Kasmi, Elise Seynaeve, Veronica Mavrovouna, Jana De Vrieze, Michael A. Brehm, Sandra Maréchal, Sophie Janssens, Florence Lambolez, Niels Hellings, Stefaan De Koker, Bieke Broux   +30 more
wiley   +1 more source

A Sting Beyond the Skin: Jellyfish Envenomation Presenting With Paralytic Ileus and Acute Urinary Retention. [PDF]

Cureus
Sivagurunathan K, Jegathesan N.
europepmc   +1 more source

α‐Synuclein Aggregate‐Disassembling Compounds Prolong Survival in a Mouse Model of Parkinson's Disease

Aggregate, Volume 7, Issue 9, September 2026.
All‐D peptides that bind monomeric α‐synuclein shift the aggregation equilibrium, dismantle pathogenic fibrils, and suppress seeding activity in vitro and in cells. In a Parkinson's disease mouse model, treatment delays disease progression and extends survival, supporting direct aggregate disassembly as a disease‐modifying therapeutic strategy for ...
Sara Reithofer, Marc Sevenich, Madita Vollmer, Dila Kurtul, Laura Müller, Pelin Özdüzenciler, Laurin Gerhards, Kira Allmeroth, Mathias Wendt, Fahimeh Charbgoo, Sarah Schemmert, Marcel Naumann, Karolina Korostov, Gina Hartmann, Lothar Gremer, Gültekin Tamgüney, Dieter Willbold, Antje Willuweit   +17 more
wiley   +1 more source

Paralysis efficiency (PD₅₀) scales linearly with lethality (LD₅₀) in spider venoms. [PDF]

Toxicon X
Lyons K, Leonard D, McSharry L, Martindale M, Collier BL, Vitkauskaite A, Dunbar JP, Dugon MM, Healy K.   +8 more
europepmc   +1 more source

Phytochemical Profiling and Biological Evaluation of Pistacia lentiscus L. grown in Chlef (Algeria): An Integrated In Vitro, In Vivo, and In Silico Study

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The antihypoxic and antioxidant activities of Pistacia lentiscus L. extract are assessed. High total phenolics and flavonoids contents are noted. Various phenolic acids and flavonoids are identified via HPLC‐MS analysis. The extract demonstrates important scavenging and reducing power, enhances mice survival under normobaric hypoxia, and reduces ...
Halima Saiah, Ali Zineddine Boumehira, Wassila Saiah, Salima Boudane, Asma Al‐farajein   +4 more
wiley   +1 more source

Comparative Analytics and Pharmacodynamics of the Complex Protein-Free Botulinum Toxin Type A Formulations DaxibotulinumtoxinA, IncobotulinumtoxinA and RelabotulinumtoxinA. [PDF]

Toxins (Basel)
Honndorf S, Kühbach K, Eisele KH, Shokurova A, Buch P, Jatzke C, Taylor HV, Fink K.   +7 more
europepmc   +1 more source

Beyond the Rash: Simultaneous Bilateral Facial Nerve Palsy Following Childhood Varicella Infection

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Bilateral facial nerve palsy is a rare neurological condition in children and is infrequently associated with primary Varicella (chickenpox) infection. We report the case of a 10‐year‐old previously healthy girl who developed simultaneous bilateral lower motor neuron facial weakness 3 weeks after a self‐limiting varicella infection.
Mohamed Sheikh Hassan, Abdiwahid Ahmed Ibrahim, Said Abdi Mohamed, Nor Osman Sidow, Said Abdirahman Ahmed, Nur Adam Mohamed, Mohamed Mukhtar Mohamed, Saadaq Adan Hussein   +7 more
wiley   +1 more source

Toxic <i>Alexandrium</i> Treatment in Western Australia: Investigating the Efficacy of Modified Nano Clay. [PDF]

Toxins (Basel)
Kwambai CS, Ennaceri H, Lymbery AJ, Laird DW, Cosgrove J, Moheimani NR.   +5 more
europepmc   +1 more source

Laryngeal NUT Carcinoma With BRD4::NUTM1 Fusion: A 4‐Year Clinical Course Highlighting the Limitations of Current Multimodal Therapy

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Nuclear protein in testis (NUT) carcinoma is a rare, aggressive malignancy driven by NUTM1 rearrangement, often misdiagnosed as squamous cell carcinoma, with no established standard therapy. This report describes the clinical course and treatment resistance in primary laryngeal NUT carcinoma and provides insights into potential ...
Masafumi Kanno, Chiai Sasaki, Eiichi Kato, Hoshino Terada, Nobuhiro Hanai, Eiichi Sasaki, Mana Fukushima, Toshiki Masuishi, Keisuke Takanari, Yasuto Fukada, Yuto Miyazaki, Yuki Sonoda, Yukinori Kato, Taiyo Morikawa, Tetsuji Takabayashi, Shigeharu Fujieda   +15 more
wiley   +1 more source