Results 81 to 90 of about 7,189,567 (273)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Transport, 2018 Due to the good mechanical performances and design flexibility of Long Glass Fiber Reinforced Polypropyl-ene (LGFRP) composite, it has been increasingly used in the automotive components, in which the LGFRP components are likely to sustain different ...
Shuyong Duan +5 more
doaj +1 more source
Estimation of Collision Impact Parameter
, 2000 We demonstrate that the nuclear collision geometry (i.e. impact parameter) can be determined with 1.5 fm accuracy in an event-by-event analysis by measuring the transverse energy flow in the pseudorapidity region $3 \le |\eta| \le 5$ with a minimal ...
Bedjidian M +17 more
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Inversion for Anisotropic Velocity Parameter [PDF]
, 1997 The problem under study concerns the robust computation of a certain parameter of anisotropy from observed travel-times of a seismic shear wave propagating through a geological medium. We have obtained an exact mathematical description of a geoseismic
Lamoureux, M.
core
k-Parameter geodesic variations
, 2011 Suppose $S$ is a semispray on a manifold $M$. We know that the complete lift $S^c$ of $S$ is a semispray on $TM$ with the property that geodesics of $S^c$ correspond to Jacobi fields of $S$.
Bucataru, Ioan, Dahl, Matias F.
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
International Journal of General Medicine, 2022 Simeon Meskele Leyto,1 Kusse Urmale Mare2 1Department of Anatomy, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia; 2Department of Nursing, College of Medicine and Health Sciences, Samara University, Samara ...
Leyto SM, Mare KU
doaj