Results 71 to 80 of about 764,789 (277)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Data-driven adaptive setting algorithm for coiling temperature model parameter

open access: yes工程科学学报, 2020
To improve the coiling temperature control accuracy for change-over strip or the first coil of batch hot-rolling, data mining technology was adopted to infer the water cooling learning coefficient which is used in coiling temperature model preset for ...
Liang-gui PENG   +4 more
doaj   +1 more source

On Adaptive Grad-Div Parameter Selection

open access: yesJournal of Scientific Computing, 2022
We propose, analyze and test a new adaptive penalty scheme that picks the penalty parameter $ε$ element by element small where $\nabla\cdot u^h$ is large. We start by analyzing and testing the new scheme on the most simple but interesting setting, the Stokes problem. Finally, we extend and test the algorithm on the incompressible Navier Stokes equation
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Adaptation of the Scaling Factor Based on the Success Rate in Differential Evolution

open access: yesMathematics
Differential evolution is a popular heuristic black-box numerical optimization algorithm which is often used due to its simplicity and efficiency. Parameter adaptation is one of the main directions of study regarding the differential evolution algorithm.
Vladimir Stanovov, Eugene Semenkin
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

An Adaptive Hyperfine Spectrum Extraction Algorithm for Optical Sensing Based on SG Filtering and VMD

open access: yesSensors
In optical sensing, signal demodulation often degrades fine spectral data, particularly in spectroscopic measurements affected by Doppler noise, aliasing, and circuit noise.
Yupeng Wu   +7 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Mamba-DQN: Adaptively Tunes Visual SLAM Parameters Based on Historical Observation DQN

open access: yesApplied Sciences
The parameter configuration of traditional visual SLAM algorithms usually relies on expert experience and extensive experiments, and the parameter configuration needs to be reset as the scene changes, which is a complex and tedious process.
Xubo Ma   +3 more
doaj   +1 more source

Automatic design of mutation parameter adaptation for differential evolution [PDF]

open access: yesITM Web of Conferences
In this paper the Efficient Global Optimization algorithm is applied to design the adaptation strategy for mutation parameter in Differential Evolution.
Vladimir Stanovov, Semenkin Eugene
doaj   +1 more source

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