Results 31 to 40 of about 201,433 (263)

Calibration of individual-based models to epidemiological data: A systematic review.

open access: yesPLoS Computational Biology, 2020
Individual-based models (IBMs) informing public health policy should be calibrated to data and provide estimates of uncertainty. Two main components of model-calibration methods are the parameter-search strategy and the goodness-of-fit (GOF) measure ...
C Marijn Hazelbag   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Calibration for Computer Models with Time-Varying Parameter

open access: yesMathematics
Traditional calibration methods often assume constant parameters that remain unchanged across input conditions, which can limit predictive accuracy when parameters actually vary.
Yang Sun, Xiangzhong Fang
doaj   +1 more source

Calibration in Temperature of Photometric Parameters [PDF]

open access: yesSymposium - International Astronomical Union, 1985
It is very easy to use a Planck distribution to show that a color index is a temperature parameter, but it is more difficult to calibrate such a color index in terms of temperature because only a few Teff values are determined. A pioneering work is that of Kuiper (1938), who derived a temperature scale according to spectral type (from A0 to M2 for ...
openaire   +1 more source

Calibration of a Manipulator With a Regularized Parameter Identification Method

open access: yesIEEE Access, 2022
As an inverse problem, the parameter identification of manipulators is essential to in-situ calibration. Since the ill-posed inverse kinematic model is sensitive to the measurement value, even tiny errors will make the geometric model of the manipulator wrongly identified.
Xuan Li   +5 more
openaire   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

A new sewage exfiltration model – parameters and calibration [PDF]

open access: yesWater Science and Technology, 2011
Exfiltration of waste water from sewer systems represents a potential danger for the soil and the aquifer. Common models, which are used to describe the exfiltration process, are based on the law of Darcy, extended by a more or less detailed consideration of the expansion of leaks, the characteristics of the soil and the colmation layer.
Christian, Karpf, Peter, Krebs
openaire   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Calibration Method for Industrial Robots Based on the Principle of Perigon Error Close

open access: yesIEEE Access, 2022
For the problem that the self-error of industrial robot calibration device has influence on calibration accuracy, a calibration method of industrial robots based on the principle of Perigon Error Close is proposed.
Xirui Li   +3 more
doaj   +1 more source

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