Results 61 to 70 of about 4,509,622 (292)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Identification-based Diagnosis of Rainfall ¿Stream Flow Data: the Tinderry Catchment [PDF]

open access: yes, 2011
System identification tools, such as transfer function (TF) model structure identification, recursive estimation, time-varying parameter (TVP) estimation and assessment of data information, are used to evaluate the quality of rainfall-stream flow data ...
Keesman, K.J., Young, P.C., Jakeman, A.
core  

Grey-box model identification via evolutionary computing [PDF]

open access: yes, 2002
This paper presents an evolutionary grey-box model identification methodology that makes the best use of a priori knowledge on a clear-box model with a global structural representation of the physical system under study, whilst incorporating accurate ...
Y. Li, Li, Y., K.C. Tan, Tan, K.C.
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Cuckoo Search Algorithm for Model Parameter Identification [PDF]

open access: yesInternational Journal Bioautomation, 2016
In this paper, the metaheuristics algorithm Cuckoo Search (CS), is adapted and applied for a model parameter identification of an E. coli fed-batch cultivation process. The dynamics of bacteria growth and substrate (glucose) utilization is described by a
Olympia Roeva, Vassia Atanassova
doaj  

Semi-analytic parameter identification for complex yield functions

open access: yesMATEC Web of Conferences, 2016
This paper presents a new parameter identification scheme for complex yield criteria of sheet metals using experimentally determined load and strain distributions and combining analytical stress analysis on sectional strain data with common inverse ...
Küsters Niklas, Brosius Alexander
doaj   +1 more source

Parameter Identification of Fractional-Order Discrete Chaotic Systems

open access: yesEntropy, 2019
Research on fractional-order discrete chaotic systems has grown in recent years, and chaos synchronization of such systems is a new topic. To address the deficiencies of the extant chaos synchronization methods for fractional-order discrete chaotic ...
Yuexi Peng   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

State Estimation-based Transmission line parameter identification

open access: yesIngeniería e Investigación, 2010
This article presents two state-estimation-based algorithms for identifying transmission line parameters. The identification technique used simultaneous state-parameter estimation on an artificial power system composed of several copies of the same ...
Fredy Andrés Olarte Dussán   +2 more
doaj  

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