Results 71 to 80 of about 4,509,622 (292)
Ship parameter identification method based on improved wild horse optimizer
Zhongguo Jianchuan YanjiuObjectiveIt is difficult to achieve comprehensive parameter identification in multiple dimensions and degrees of freedom using traditional parameter identification methods.
Zhigang QI, Hao ZHANG, Bing LI, Zhe LU
doaj +1 more source
A parameter identification problem in stochastic homogenization
ESAIM: Proceedings and Surveys, 2015 In porous media physics, calibrating model parameters through experiments is a challenge. This process is plagued with errors that come from modelling, measurement and computation of the macroscopic observables through random ...
Legoll Frédéric +3 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Robust Design of Parameter Identification [PDF]
, 2017 Quality of results computed during parameter identification problems relies on the selection of system's states while performing measurements. This choice usually does not take into account the uncertainty of states and of measures. For identifiability, classical methods focus only on the contribution of model errors on the uncertainty of parameters ...
Massein, Aurélien +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Identification of a nonlinear dynamic biological model using the dominant parameter selection method
, 2010 The identification of nonlinear models sometimes encounters problems because of the limited amount of available measurements in combination with a large number of uncertain model parameters to be identified.
Gutman Per-O +2 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Identification of Driver Model Parameters [PDF]
International Journal of Occupational Safety and Ergonomics, 2001 The paper presents a driver model, which can be used in a computer simulation of a curved ride of a car. The identification of the driver parameters consisted in a comparison of the results of computer calculations obtained for the driver-vehicle-environment model with different driver data sets with test results of the double lane-change manoeuvre ...
openaire +2 more sources
Dynamic Parameter Identification of Hydrodynamic Bearing-Rotor System
Shock and Vibration, 2015 A new method called modal parameter genetic time domain identification was employed to study the characteristics of the bearing-rotor system. A multifrequency signal decomposition technology to identify the main components of the measured signal and ...
Zhiqiang Song, Yunhe Liu
doaj +1 more source