Results 81 to 90 of about 1,806,131 (303)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Dynamic Parameter Identification of Hydrodynamic Bearing-Rotor System
Shock and Vibration, 2015 A new method called modal parameter genetic time domain identification was employed to study the characteristics of the bearing-rotor system. A multifrequency signal decomposition technology to identify the main components of the measured signal and ...
Zhiqiang Song, Yunhe Liu
doaj +1 more source
Parameter identification in continuum models [PDF]
Approximation techniques for use in numerical schemes for estimating spatially varying coefficients in continuum models such as those for Euler-Bernoulli beams are discussed.
Banks, H. T., Crowley, J. M.
core +1 more source
Preprocessing of Prithvi Post Flight data for Parameter Identification [PDF]
, 1989 This document presents the methods of preprocessing flight data . The data acquired during flight test contain data spikes and- noise, due to various reasons and requires processing .
Raol, JR, Santhakumar, N
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Frontiers in Energy ResearchAccurate line-parameter identification is an important foundation for refined the regulation, protection, and control of distribution systems. Traditional identification models provide accurate modeling, while conventional identification approaches are ...
Xuebao Jiang +5 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Semi-analytic parameter identification for complex yield functions
MATEC Web of Conferences, 2016 This paper presents a new parameter identification scheme for complex yield criteria of sheet metals using experimentally determined load and strain distributions and combining analytical stress analysis on sectional strain data with common inverse ...
Küsters Niklas, Brosius Alexander
doaj +1 more source
Location of leaks in pipelines using parameter identification tools [PDF]
, 2017 This work proposes an approach to locate leaks by identifying the parameters of finite models associated with these fault events. The identification problem is attacked by using well-known identification methods such as the Prediction Error Method and ...
Torres, L.
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source