Results 51 to 60 of about 1,939,164 (288)

Machine learning assisted prediction and optimisation of quality for laser directed energy deposition

Virtual and Physical Prototyping
Laser-directed energy deposition (L-DED) using a fibre laser involves complex parameter-quality relationships, and inappropriate parameter selection may cause porosity and unstable geometry.
Ao Liu, Xingyu Jiang, Shuhao Wang, Dan Liu, Guozhe Yang, Shun Liu, Chee Kai Chua   +6 more
doaj   +1 more source

Bayesian hyper-parameter optimisation for malware detection [PDF]

, 2022
Malware detection is a major security concern and has been the subject of a great deal of research and development. Machine learning is a natural technology for addressing malware detection, and many researchers have investigated its use.
ALGorain, F.T., John A. Clark, Clark, J.A., Fahad T. ALGorain   +3 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Multi-Scenario Resistance Optimisation of an Indonesian Pioneer Vessel Through Response Surface Method

Fluids
Improving ship hydrodynamic efficiency is an important strategy for reducing fuel consumption and operational costs. This study investigates the optimisation of ship resistance through a combined approach involving hull form modification and operational ...
Muhammad Iqbal, Andi Trimulyono, Ammarunissa Noor Asiyah Raihannanda, Azka Maulana Widestra, Berlian Arswendo Adietya, Ahmad Firdhaus   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Robust multi-objective calibration strategies – possibilities for improving flood forecasting [PDF]

Hydrology and Earth System Sciences, 2012
Process-oriented rainfall-runoff models are designed to approximate the complex hydrologic processes within a specific catchment and in particular to simulate the discharge at the catchment outlet. Most of these models exhibit a high degree of complexity
G. H. Schmitz, P. Saile, J. Cullmann, T. Krauße   +3 more
doaj   +1 more source

Cross validation score for each fold during training and parameter optimisation.

, 2023
Cross validation score for each fold during training and parameter optimisation.
Adhiraj Nath (17118269), Utpal Bora (2589871)   +1 more
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Wind resistance and deflection-based design of aluminium panel curtain walls with panel-stiffener support systems

Materials Research Express
Aluminium panel curtain walls are widely used in building envelopes, but the quantitative selection of panel and stiffener parameters remains insufficiently established.
Dongbao Shi, Wang Yujie
doaj   +1 more source