Results 61 to 70 of about 1,939,164 (288)
EnergiesThe development of energy storage systems is significant for solving problems related to climate change. A hybrid energy storage system (HESS), combining batteries with ultracapacitors, may be a feasible way to improve the efficiency of electric vehicles
Adrian Chmielewski +8 more
doaj +1 more source
Results from parameter optimisation for HC-RNN with various activation functions and learning rates.
, 2023 Results from parameter optimisation for HC-RNN with various activation functions and learning rates.
Kristin Tøndel (6549560) +1 more
core +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Results from parameter optimisation for HC-CNN with various activation functions and learning rates.
, 2023 Results from parameter optimisation for HC-CNN with various activation functions and learning rates.
Kristin Tøndel (6549560) +1 more
core +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Robust Parameter Optimisation of Noise-Tolerant Clustering for DENCLUE Using Differential Evolution
MathematicsClustering samples based on similarity remains a significant challenge, especially when the goal is to accurately capture the underlying data clusters of complex arbitrary shapes.
Omer Ajmal +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
IonBench: A benchmark of optimisation strategies for mathematical models of ion channel currents.
PLoS Computational BiologyIon channel models present many challenging optimisation problems. These include unidentifiable parameters, noisy data, unobserved states, and a combination of both fast and slow timescales.
Matt J Owen, Gary R Mirams
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
BuildingsUnderground space development is a crucial approach to addressing traffic congestion in China’s cities, especially through underground construction. However, the traditional pit internal support system, particularly the concrete internal support system ...
Ye Pan +7 more
doaj +1 more source