Results 81 to 90 of about 811,356 (270)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Robust Bayesian inference in Iq-Spherical models [PDF]
, 1992 The class of multivariate lq-spherical distributions is introduced and defined through their isodensity surfaces. We prove that, under a Jeffreys' type improper prior on the scale parameter, posterior inference on the location parameters is the same for
Osiewalski, Jacek, Steel, Mark F.J.
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Normalized Robust FOPID Controller Regulation Based on Small Gain Theorem
Complexity, 2018 In this paper, a normalized robust FOPID controller regulation algorithm is proposed. Only one parameter k is necessary to be tuned in the controller regulation process, so the proposed control algorithm is convenient to be applied on both fractional ...
Shuo Zhang, Lu Liu
doaj +1 more source
Stability, convergence, and robustness of deterministic multivariable self-tuning control
工程科学学报, 2019 Self-tuning control is an important approach to intelligent control system design because this kind of control system uses online parameter estimation (or learning) to derive the model of the plant, and as a result of model parameter estimation (or ...
ZHAO Li, ZHANG Wei-cun, CHU Tian-guang
doaj +1 more source
Robust on-off pulse control of flexible space vehicles [PDF]
The on-off reaction jet control system is often used for attitude and orbital maneuvering of various spacecraft. Future space vehicles such as the orbital transfer vehicles, orbital maneuvering vehicles, and space station will extensively use reaction ...
Sinha, Ravi, Wie, Bong
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Journal of Advances in Modeling Earth Systems, 2019 Dynamical environmental systems models are highly parameterized, having large numbers of parameters whose values are uncertain. For spatially distributed continental‐scale applications, such models must be run for very large numbers of grid locations. To
Xueli Huo +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Testing for cointegration using induced-order statistics. [PDF]
In this paper we explore the usefulness of induced-order statistics in the characterization of integrated series and of cointegration relationships. We propose a non-parametric test statistic for testing the null hypothesis of two independent random ...
Escribano, Álvaro +2 more
core