Results 51 to 60 of about 5,756,257 (288)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Iris: Deep Space Small Satellite Radio [PDF]

open access: yes, 2017
With nanosatellites being used for deep space missions, the need for a unique communications architecture to relay valuable mission data back to NASA’s Deep Space Network (DSN) is ...
Space Dynamics Laboratory
core   +1 more source

A Computer Algebra Approach to Linear ODE Systems with Parametric Coefficients [PDF]

open access: yesControl and Optimization in Applied Mathematics
This paper analyzes systems of linear first-order ordinary differential equations (ODEs) with parametric coefficients, a class of problems that arises in control theory, optimization, and applied mathematics.
Mahdi Dehghani Darmian
doaj   +1 more source

Expanding the parameter space of natural supersymmetry

open access: yesJournal of High Energy Physics, 2020
SUSY/SUGRA models with naturalness defined via small μ are constrained due to experiment on the relic density and the experimental limits on the WIMP-proton cross-section and WIMP annihilation cross-section from indirect detection experiments ...
Amin Aboubrahim, Wan-Zhe Feng, Pran Nath
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Parameter Identifiability for Nonlinear LPV Models

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2022
Linear parameter varying (LPV) models are being increasingly used as a bridge between linear and nonlinear models. From a mathematical point of view, a large class of nonlinear models can be rewritten in LPV or quasi-LPV forms easing their analysis. From
Srinivasarengan Krishnan   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Dynamics of a Uniparametric Sixth-Order Family for Multiple Roots with Rational-Polynomial Weight Functions

open access: yesAxioms
In this study, we have performed a comprehensive dynamical assessment of a sixth-order parametric family of iterative methods for computing multiple roots of nonlinear equations.
Young Hee Geum
doaj   +1 more source

Exceptional cones in 4D parameter space

open access: yesOptics Express, 2020
The notion of synthetic dimensions has expanded the realm of topological physics to four dimensional (4D) space lately. In this work, non-Hermiticity is used as a synthetic parameter in PT-symmetric photonic crystals to study the topological physics in 4D non-Hermitian synthetic parameter space. We realize a 3D exceptional hypersurface (EHS) in such 4D
Qiang Wang   +4 more
openaire   +4 more sources

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