Results 71 to 80 of about 11,534,535 (349)

occumb: An R package for site occupancy modeling of eDNA metabarcoding data

open access: yesPopulation Ecology, EarlyView.
This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley   +1 more source

Parameters in Banach spaces and orthogonality

open access: yesConstructive Mathematical Analysis, 2022
In Banach spaces, plenty of parameters have been considered: they are often defined by using pairs of vectors. Rarely, they are defined by considering pairs of vectors which are orthogonal in the sense of Birkhoff and James; in that case the study is often not easy.
Pier Luigi Papini, Marco Barontı
openaire   +2 more sources

Bootstrapping Parameter Space Exploration for Fast Tuning

open access: yesInternational Conference on Supercomputing, 2018
The task of tuning parameters for optimizing performance or other metrics of interest such as energy, variability, etc. can be resource and time consuming. Presence of a large parameter space makes a comprehensive exploration infeasible.
Jayaraman J. Thiagarajan   +9 more
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Exploring Parameter Space in Reinforcement Learning

open access: yesPaladyn, 2010
This paper discusses parameter-based exploration methods for reinforcement learning. Parameter-based methods perturb parameters of a general function approximator directly, rather than adding noise to the resulting actions.
Rückstieß Thomas   +5 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Type space on a purely measurable parameter space [PDF]

open access: yesEconomic Theory, 2005
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

Parameter synthesis for Markov models: covering the parameter space [PDF]

open access: yesFormal Methods in System Design
AbstractMarkov chain analysis is a key technique in formal verification. A practical obstacle is that all probabilities in Markov models need to be known. However, system quantities such as failure rates or packet loss ratios, etc. are often not—or only partially—known.
Junges, Sebastian   +6 more
openaire   +6 more sources

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