Results 51 to 60 of about 1,153,922 (283)

Parametrizations for Families of ECM-Friendly Curves [PDF]

Proceedings of the 2017 ACM International Symposium on Symbolic and Algebraic Computation, 2017
We provide a new family of elliptic curves that results in a one to two percent performance improvement of the elliptic curve integer factoriza-tion method. The speedup is confirmed by extensive tests for factors ranging from 15 to 63 bits.
Gélin, Alexandre, Kleinjung, Thorsten, Lenstra, Arjen K.   +2 more
openaire   +5 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Real parametrization of algebraic curves [PDF]

, 1998
There are various algorithms known for deciding the parametrizability (rationality) of a plane algebraic curve, and if the curve is rational, actually computing a parametrization. Optimality criteria such as low degrees in the parametrization or low degree field extensions are met by some parametrization algorithms.
J. Rafael Sendra, Franz Winkler 0001
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Generating Algorithm for High Order Curve Based on ACO

ITM Web of Conferences, 2017
A generating algorithm for parametric curve based on ant colony optimization is proposed in this paper. In order to produce the maximum step efficiently, the ant colony optimization is used to search the optimal step of curve in forward.
Li Zhi-Jie, Duan Xiao-Dong, Lu Bo, Yun Jian   +3 more
doaj   +1 more source

Roullete curves, coin paradox and Aristotle’s wheel paradox [PDF]

Revista Brasileira de Ensino de Física
This work discusses the concept of roulette, the generated curves that occur when one curve rolls without slipping along another, tracing the path of a fixed point.
Osvaldo L. Santos-Pereira
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Minimax properties of Fréchet means of discretely sampled curves [PDF]

, 2012
We study the problem of estimating a mean pattern from a set of similar curves in the setting where the variability in the data is due to random geometric deformations and additive noise.
Gendre, Xavier, Xavier Gendre, Bigot, Jérémie, Jérémie Bigot   +3 more
core   +1 more source

A Bayesian non-parametric mixed-effects model of microbial growth curves.

PLoS Computational Biology, 2020
Substantive changes in gene expression, metabolism, and the proteome are manifested in overall changes in microbial population growth. Quantifying how microbes grow is therefore fundamental to areas such as genetics, bioengineering, and food safety ...
Peter D Tonner, Cynthia L Darnell, Francesca M L Bushell, Peter A Lund, Amy K Schmid, Scott C Schmidler   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source