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Journal of DaylightingParametric design is one of the thriving contemporary architectural treatments that not only has an influence on the design of building envelopes but is capable of affecting the users physically and psychologically.
Yasmine Mahmoud Saad Abdelhamid +2 more
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Learning Parametric Designing [PDF]
, 2012 Parametric designing, its instruments, and techniques move architectural design education towards novel avenues of deep learning. Akin to learning and working environments of engineering and manufacturing, it offers similar advantages for architects. Yet it is not as simple as using another tool; parametric designing fundamentally shifts the engagement
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Computer-Aided Modeling In Parametric Landscape Design
Düzce University Faculty of Forestry Journal of ForestryIn this study, the possibilities of using parametric design in landscape architecture are examined through the design process and design elements. Three different computer-aided design programs, which play an important role in parametric design, were ...
Fazilet Muhammed Çolak +1 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Automatic structural design by a set-based parametric design method
Automation in Construction, 2019 Modern structural design faces new challenges, such as addressing the needs of several stakeholders and satisfying the criteria for achieving sustainability. The traditional design process does not allow resolution of these challenges.
R. Rempling +3 more
semanticscholar +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Characteristics and Application Analysis of Building Design Based on Parametric BIM [PDF]
, 2022 Xiaojing Yu
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Application of Freeform Surface to the Parametric Design of Plate Sheet Structure
Chemical Engineering Transactions, 2018 This paper constructs a small-scale, lightweight structure with complex freeform surfaces via parametric design. First, the method of freeform surface modelling and parametric design were introduced, and combined into the parametric design aided freeform
Wei Zhang +3 more
doaj +1 more source