Results 71 to 80 of about 14,108,193 (356)

Parametric Output Feedback Controller Design

open access: yesIFAC Proceedings Volumes, 1987
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Roppenecker, Guenter, O'Reilly, John
openaire   +2 more sources

Parametric design of graded truss lattice structures for enhanced thermal dissipation

open access: yesComput. Aided Des., 2019
Truss lattice structures are intricate geometries, whose fabrication has recently been simplified by the development of Additive Manufacturing (AM) technologies. These lightweight geometries present great volume densities and surface-to-occupancy ratios,
Benjamin Vaissier   +3 more
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Modelo paramétrico de pórticos em concreto armado com dimensionamento otimizado: uma proposta de ferramenta de projeto para as fases iniciais de concepção estrutural

open access: yesAmbiente Construído
Resumo Comumente, a concepção de sistema estrutural e seu projeto preliminar deveriam estar nos estágios iniciais do desenvolvimento do projeto da forma arquitetônica.
Felipe Tavares da Silva
doaj   +1 more source

Parametric design of garment pattern based on body dimensions

open access: yesInternational Journal of Industrial Ergonomics, 2019
Garment pattern-making is one of the most important parts in fashion design and production. However, the traditional pattern-making is an experience based work and very time-consuming.
Kaixuan Liu   +4 more
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Exploring Parametric Concepts and Principles for Furniture and Interior Design

open access: yesInteriority
This research explores the incorporation of parametric models into the algorithmic design process, specifically focusing on furniture and interior design. It presents a case of an experimental equation centred around a waffle honeycomb structure.
Klawkanlayaphon Sawatmongkhonkul   +2 more
doaj   +1 more source

Parametric Design in Timber Gridshell Tectonics

open access: yesSHS Web of Conferences, 2018
This paper begins with a simple proposition: rather than mimicking the geometric structures found in nature, perhaps the most effective modes of sustainable fabrication can be found throughunderstanding the nature of materials themselves.
Ismailiyah Al Athas Syarifah
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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