Results 51 to 60 of about 4,338,901 (297)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hypothesis: Property-Based Testing for Python
, 2021 The "@example(...)" decorator now has a ".via()" method, which future tools will use to track automatically-added covering examples (issue 3506). The canonical version of these notes (with links) is on readthedocs.If you use Hypothesis as part of a ...
MacIver, David R. +2 more
core +1 more source
Hypothesis testing for an entangled state produced by spontaneous parametric down-conversion [PDF]
Physical Review A, 2006 Generation and characterization of entanglement are crucial tasks in quantum information processing. A hypothesis testing scheme for entanglement has been formulated. Three designs were proposed to test the entangled photon states created by the spontaneous parametric down conversion.
Hayashi, Masahito +5 more
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Objective Bayes estimation and hypothesis testing : the reference-intrinsic approach [PDF]
, 2005 Conventional frequentist solutions to point estimation and hypothesis testing typically need ad hoc modifications when dealing with non-regular models, and may prove to be misleading.
Juárez, Miguel A.
core
Muallimuna: Jurnal Madrasah IbtidaiyahThis research aims to determine the effect of using augmented reality media on increasing understanding of social studies learning concepts in elementary schools. This research is a quantitative research with a quasi-experimental design, namely a type of
Nur Fajrina +2 more
doaj +1 more source
Model Averaging with AIC Weights for Hypothesis Testing of Hormesis at Low Doses
Dose-Response, 2017 For many dose–response studies, large samples are not available. Particularly, when the outcome of interest is binary rather than continuous, a large sample size is required to provide evidence for hormesis at low doses. In a small or moderate sample, we
Steven B. Kim, Nathan Sanders
doaj +1 more source