Results 101 to 110 of about 566,253 (298)

Parametric resonance brain model

Scientific Reports
The paper introduces a parametric resonance model for characterizing some features of the brain's electrical activity. This activity is assumed to be a fundamental aspect of brain functionality underpinning functions from basic sensory processing to complex cognitive operations such as memory, reasoning, and emotion.
Salvatore Magazù, Maria Teresa Caccamo
openaire   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Numerical modeling of underwater parametric propagation to detect buried objects [PDF]

, 2011
In underwater acoustics, detection of buried objects in sediments (cables, mines,…) is a complex problem. One reason is that acoustic attenuation in these sediments increases with frequency. To ensure sufficient penetration depth in marine sediments, low
BOU MATAR, Olivier, BOUTTARD, Etienne, LABAT, Valérie   +2 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Sketch-based and parametric modeling: Association of two-externalization processes for early daylight optimization [PDF]

, 2015
peer reviewedThis paper focuses on sketch-based and parametric modeling as two externalization devices used in architectural design practice. The first part of this paper addresses features and ability of these externalization tools to support design ...
Delfosse, Vincent, Gallas, Mohamed Anis
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Impact of Thermal Mass, Window Performance, and Window–Wall Ratio on Indoor Thermal Dynamics in Public Buildings

Buildings
Thermal comfort in public buildings is crucial for occupant well-being and energy efficiency. This study employs TRNSYS software to simulate the effects of thermal mass, window performance, and window–wall ratio (WWR) on summer thermal comfort.
Ran Cheng, Nan Zhang, Wengan Zhang, Yinan Sun, Bing Yin, Weijun Gao   +5 more
doaj   +1 more source

Parametric modeling and analysis of intake phases for side-ported Wankel rotary engines. [PDF]

Heliyon, 2023
Wang H, Ji C, Yang J, Ge Y, Zambalov S, Yakovlev I.   +5 more
europepmc   +1 more source

Circular Bernstein polynomial distributions [PDF]

This paper introduces a new non-parametric approach to the modeling of circular data, based on the use of Bernstein polynomial densities which generalizes the standard Bernstein polynomial model to account for the specific characteristics of circular ...
Concepción Ausín, José Antonio Carnicero, Michael P. Wiper   +2 more
core