Results 81 to 90 of about 566,253 (298)

Short and long-term wind turbine power output prediction [PDF]

open access: yes, 2017
In the wind energy industry, it is of great importance to develop models that accurately forecast the power output of a wind turbine, as such predictions are used for wind farm location assessment or power pricing and bidding, monitoring, and preventive ...
Kapodistria, Stella   +2 more
core   +2 more sources

A Semiparametric Bayesian Model for Detecting Synchrony Among Multiple Neurons

open access: yes, 2014
We propose a scalable semiparametric Bayesian model to capture dependencies among multiple neurons by detecting their co-firing (possibly with some lag time) patterns over time.
Behseta, Sam   +5 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

A Component-based Software Development and Execution Framework for CAx Applications

open access: yesActa Polytechnica, 2004
Digitalization of the manufacturing process and technologies is regarded as the key to increased competitive ability. The MZ-Platform infrastructure is a component-based software development framework, designed for supporting enterprises to enhance ...
N. Matsuki, H. Tokunaga, H. Sawada
doaj  

Multi-objective optimization and characteristic analysis of contra-rotating fan double-row blades coupling

open access: yesMeikuang Anquan
To enhance the aerodynamic performance of contra-rotating fan and ensure the safe working environment of mine, based on feedforward neural network agent model and genetic algorithm, the multi-objective optimization of contra-rotating fan double-row ...
Xinyu ZHANG, Hua JIANG, Wuqi GONG
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Resistance welding parametric modeling based on CATIA CAA

open access: yesJournal of Hebei University of Science and Technology, 2019
There′re numbers of welding spots and types in vehicle seat framework (VSF) and high welding quality requirement, while commercial CAD weld design has low efficiency and cannot satisfy customers′ requirement, so it′s urgent to realize automated ...
Huawei CHEN   +3 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

DeepCoder: Semi-parametric Variational Autoencoders for Automatic Facial Action Coding

open access: yes, 2017
Human face exhibits an inherent hierarchy in its representations (i.e., holistic facial expressions can be encoded via a set of facial action units (AUs) and their intensity).
Eleftheriadis, Stefanos   +5 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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