Differential Features of Fusion Activation within the Paramyxoviridae [PDF]
Paramyxovirus (PMV) entry requires the coordinated action of two envelope glycoproteins, the receptor binding protein (RBP) and fusion protein (F). The sequence of events that occurs during the PMV entry process is tightly regulated.
Kristopher D. Azarm, Benhur Lee
doaj +5 more sources
Henipavirus in Northern Short-Tailed Shrew, Alabama, USA [PDF]
RNA metagenomic analysis of tissues from 4 wild-caught northern short-tailed shrews in Alabama, USA, revealed a novel henipavirus (family Paramyxoviridae).
Rhys H. Parry +9 more
doaj +3 more sources
Probable Human Infection with a Newly Described Virus in the Family Paramyxoviridae
After an apparently new virus in the family Paramyxoviridae was isolated from pigs in August 1997, an investigation was carried out to assess its risk for humans.
Kerry Chant +4 more
doaj +2 more sources
Mumps is an infectious disease controlled by specific vaccine prophylaxis. To date, its social and epidemiological significance remains high. This is evidenced by the process of developing and implementing into the health care practices of many countries
T. S. Chekhlyaeva +4 more
doaj +3 more sources
Monitoring the circulation of the measles virus and studying its genetic diversity is an important component of the measles elimination program. A methodological approach to molecular genetic studies and their interpretation in the measles surveillance ...
Tatiana S. Rubalskaia +4 more
doaj +3 more sources
Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High-Throughput Sequencing Data Mining. [PDF]
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Wang H +19 more
europepmc +2 more sources
Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo. [PDF]
The early host response to pathogens is mediated by several distinct pattern recognition receptors. Cytoplasmic RNA helicases including RIG-I and MDA5 have been shown to respond to viral RNA by inducing interferon (IFN) production.
Leonid Gitlin +6 more
doaj +3 more sources
Molecular detection and genomic characterization of Samak Micromys paramyxovirus-1 and -2 in Micromys minutus, Republic of Korea [PDF]
Background The discovery of viruses in small mammalian populations, particularly rodents, has expanded the family Paramyxoviridae. The overlap in habitats between rodents and humans increases the risk of zoonotic events, underscoring the importance of ...
Augustine Natasha +15 more
doaj +2 more sources
An Apparently New Virus (Family Paramyxoviridae) Infectious for Pigs, Humans, and Fruit Bats
We isolated an apparently new virus in the family Paramyxoviridae from stillborn piglets with deformities at a piggery in New South Wales, Australia. In 1997, the pregnancy rate and litter size at the piggery decreased markedly, while the proportion of ...
Adrian W. Philbey +8 more
doaj +2 more sources
Type I and Type II Interferon Antagonism Strategies Used by Paramyxoviridae: Previous and New Discoveries, in Comparison [PDF]
Paramyxoviridae is a viral family within the order of Mononegavirales; they are negative single-strand RNA viruses that can cause significant diseases in both humans and animals.
Giuseppe Pisanelli +3 more
doaj +2 more sources

