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The Evolutionary and Epidemiological Dynamics of the Paramyxoviridae [PDF]
Journal of Molecular Evolution, 2008 Paramyxoviruses are responsible for considerable disease burden in human and wildlife populations: measles and mumps continue to affect the health of children worldwide, while canine distemper virus causes serious morbidity and mortality in a wide range of mammalian species.
Laura W. Pomeroy +2 more
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Problems of classification in the family Paramyxoviridae [PDF]
Archives of Virology, 2018 A number of unassigned viruses in the family Paramyxoviridae need to be classified either as a new genus or placed into one of the seven genera currently recognized in this family. Furthermore, numerous new paramyxoviruses continue to be discovered. However, attempts at classification have highlighted the difficulties that arise by applying historic ...
B. K. Rima +9 more
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Significant differences in nucleocapsid morphology within the Paramyxoviridae
Journal of General Virology, 2002 Nucleocapsid (N) proteins from representative viruses of three genera within the Paramyxoviridae were expressed in insect cells using recombinant baculoviruses. RNA-containing structures, which appear morphologically identical to viral nucleocapsids, were isolated and subsequently imaged under a transmission electron microscope.
David Bhella +3 more
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Differential Features of Fusion Activation within the Paramyxoviridae [PDF]
Viruses, 2020 Paramyxovirus (PMV) entry requires the coordinated action of two envelope glycoproteins, the receptor binding protein (RBP) and fusion protein (F). The sequence of events that occurs during the PMV entry process is tightly regulated. This regulation ensures entry will only initiate when the virion is in the vicinity of a target cell membrane.
Kristopher D. Azarm, Benhur Lee
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Efficient and Robust Paramyxoviridae Reverse Genetics Systems [PDF]
mSphere, 2017 The ability to manipulate the genome of paramyxoviruses and evaluate the effects of these changes at the phenotypic level is a powerful tool for the investigation of specific aspects of the viral life cycle and viral pathogenesis. However, reverse genetics systems for paramyxoviruses are notoriously inefficient, when successful.
Shannon M. Beaty +9 more
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Molecular Evolution of the Paramyxoviridae and Rhabdoviridae Multiple-Protein-Encoding P Gene [PDF]
Molecular Biology and Evolution, 2000 Presented here is an analysis of the molecular evolutionary dynamics of the P gene among 76 representative sequences of the Paramyxoviridae and Rhabdoviridae RNA virus families. In a number of Paramyxoviridae taxa, as well as in vesicular stomatitis viruses of the Rhabdoviridae, the P gene encodes multiple proteins from a single genomic RNA sequence ...
I. King Jordan +2 more
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ICTV Virus Taxonomy Profile: Paramyxoviridae
Journal of General Virology, 2019 The family Paramyxoviridae consists of large enveloped RNA viruses infecting mammals, birds, reptiles and fish. Many paramyxoviruses are host-specific and several, such as measles virus, mumps virus, Nipah virus, Hendra virus and several parainfluenza viruses, are pathogenic for humans.
B. K. Rima +10 more
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Nipah virus infection: preparedness for the pathological diagnosis of an emerging Paramyxoviridae disease with epidemic potential [PDF]
Rev Inst Med Trop Sao PauloCinthya dos Santos Cirqueira +13 more
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