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ICTV Virus Taxonomy Profile: Paramyxoviridae [PDF]
The family Paramyxoviridae consists of large enveloped RNA viruses infecting mammals, birds, reptiles and fish. Many paramyxoviruses are host-specific and several, such as measles virus, mumps virus, Nipah virus, Hendra virus and several parainfluenza viruses, are pathogenic for humans.
Ron Fouchier +2 more
exaly +6 more sources
Significant differences in nucleocapsid morphology within the Paramyxoviridae
Nucleocapsid (N) proteins from representative viruses of three genera within the Paramyxoviridae were expressed in insect cells using recombinant baculoviruses. RNA-containing structures, which appear morphologically identical to viral nucleocapsids, were isolated and subsequently imaged under a transmission electron microscope.
David, Bhella +3 more
core +10 more sources
Problems of classification in the family Paramyxoviridae [PDF]
A number of unassigned viruses in the family Paramyxoviridae need to be classified either as a new genus or placed into one of the seven genera currently recognized in this family. Furthermore, numerous new paramyxoviruses continue to be discovered. However, attempts at classification have highlighted the difficulties that arise by applying historic ...
Rima, B +9 more
openaire +3 more sources
Differential Features of Fusion Activation within the Paramyxoviridae
Paramyxovirus (PMV) entry requires the coordinated action of two envelope glycoproteins, the receptor binding protein (RBP) and fusion protein (F). The sequence of events that occurs during the PMV entry process is tightly regulated.
Kristopher D. Azarm, Benhur Lee
doaj +2 more sources
Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo. [PDF]
The early host response to pathogens is mediated by several distinct pattern recognition receptors. Cytoplasmic RNA helicases including RIG-I and MDA5 have been shown to respond to viral RNA by inducing interferon (IFN) production.
Leonid Gitlin +6 more
doaj +3 more sources
Probable Human Infection with a Newly Described Virus in the Family Paramyxoviridae
After an apparently new virus in the family Paramyxoviridae was isolated from pigs in August 1997, an investigation was carried out to assess its risk for humans.
Kerry Chant +4 more
doaj +2 more sources
An Apparently New Virus (Family Paramyxoviridae) Infectious for Pigs, Humans, and Fruit Bats [PDF]
We isolated an apparently new virus in the family Paramyxoviridae from stillborn piglets with deformities at a piggery in New South Wales, Australia. In 1997, the pregnancy rate and litter size at the piggery decreased markedly, while the proportion of ...
Adrian W. Philbey +8 more
doaj +2 more sources
Healthy pangolin virome reveals mammalian viral diversity and zoonotic risk [PDF]
Background Pangolins, the world’s most trafficked mammals, have emerged as critical subjects of study due to their potential role as intermediate hosts for zoonotic viruses.
Tianyi Dong +17 more
doaj +2 more sources
Members of the family Paramyxoviridae cause most devastating diseases of animals and humans. In particular, the viruses causing rinderpest, canine distemper, Newcastle disease, measles, and mumps have arguably caused more morbidity and mortality than any other single group of related viruses in history.
Bonvicini, Francesca
core +3 more sources
Functional Analysis of the Fusion and Attachment Glycoproteins of Mojiang Henipavirus
Mojiang virus (MojV) is the first henipavirus identified in a rodent and known only by sequence data, whereas all other henipaviruses have been isolated from bats (Hendra virus, Nipah virus, Cedar virus) or discovered by sequence data from material of ...
Sofia Cheliout Da Silva +6 more
doaj +1 more source

