Differential Features of Fusion Activation within the Paramyxoviridae [PDF]
Viruses, 2020 Paramyxovirus (PMV) entry requires the coordinated action of two envelope glycoproteins, the receptor binding protein (RBP) and fusion protein (F). The sequence of events that occurs during the PMV entry process is tightly regulated.
Kristopher D. Azarm, Benhur Lee
doaj +3 more sources
Efficient and Robust
mSphere, 2017 The notoriously low efficiency of Paramyxoviridae reverse genetics systems has posed a limiting barrier to the study of viruses in this family. Previous approaches to reverse genetics have utilized a wide variety of techniques to overcome the technical ...
Shannon M. Beaty +9 more
doaj +3 more sources
The Changing Landscape of Respiratory Syncytial Virus Infections
Pathogens, 2023 Respiratory syncytial virus (RSV), a negative-sense, enveloped RNA virus of the family Paramyxoviridae, subfamily Pneumovirinae, and genus Pneumovirus, is the single most important respiratory pathogen affecting infants and young children [...]
Reinout A. Bem, Job B. M. van Woensel
doaj +1 more source
CryoEM structure of the Nipah virus nucleocapsid assembly.
PLoS Pathogens, 2021 Nipah and its close relative Hendra are highly pathogenic zoonotic viruses, storing their ssRNA genome in a helical nucleocapsid assembly formed by the N protein, a major viral immunogen.
De-Sheng Ker +3 more
doaj +1 more source
Parenteral vaccination of mammalian livestock with Newcastle disease virus-based vector vaccines offers optimal efficacy and safety [PDF]
, 2011 Newcastle disease virus (NDV) is an avian virus that is being evaluated as a vaccine vector for the delivery of foreign genes in mammals. The use of NDV as a vaccine vector in these species offers two major advantages.
Antonis, A.F.G. +3 more
core +8 more sources
Nipah virus infection and characteristics: A Review [PDF]
Journal of Bioscience and Applied ResearchA single-stranded RNA virus belonging to the Paramyxoviridae family, the Nipah virus (NiV) is extremely pathogenic. Since 2001, it has caused numerous outbreaks in Bangladesh, India, Singapore, Malaysia, and other countries.
Jinu Rajan +2 more
doaj +1 more source
Animals, 2020 Canine distemper is a contagious infectious disease, caused by canine distemper virus (CDV) belonging to Morbillivirus genus, Paramyxoviridae family, representing a serious threat for domestic and wild carnivores [...]
Cristina E. Di Francesco +2 more
doaj +1 more source
Innate Intracellular Antiviral Responses Restrict the Amplification of Defective Virus Genomes of Parainfluenza Virus 5. [PDF]
, 2020 During the replication of parainfluenza virus 5 (PIV5), copyback defective virus genomes (DVGs) are erroneously produced and are packaged into "infectious" virus particles.
Goodbourn, S +6 more
core +3 more sources
The respiratory syncytial virus nucleoprotein–RNA complex forms a left-handed helical nucleocapsid [PDF]
, 2013 Respiratory Syncytial Virus (RSV) is an important human pathogen. Its nucleocapsid (NC), which comprises the negative sense RNA viral genome coated by the viral nucleoprotein N, is a critical assembly that serves as template for both mRNA synthesis and ...
Bhella +10 more
core +3 more sources
Human Metapneumovirus Infection among Children, Bangladesh
Emerging Infectious Diseases, 2007 We confirmed circulation of human metapneumovirus (HMPV) among children with febrile and respiratory illness in an urban slum in Dhaka, Bangladesh, during active surveillance in 2001.
W. Abdullah Brooks +9 more
doaj +1 more source