Results 31 to 40 of about 13,336 (190)
Small Molecule Inhibition of Mononegavirales RNA Polymerases. [PDF]
J Med VirolABSTRACT The order Mononegavirales includes several non‐segmented negative‐sense RNA viruses that are significant human pathogens, whose transcription and replication depend on multifunctional RNA‐dependent RNA polymerase (L protein). Recent discoveries in cryo‐electron microscopy (cryo‐EM) have elucidated the structures of these polymerases and their ...
Cao CR, Mohammed M, Yang G, Wang D.
europepmc +2 more sources
Animals, 2020 Canine distemper is a contagious infectious disease, caused by canine distemper virus (CDV) belonging to Morbillivirus genus, Paramyxoviridae family, representing a serious threat for domestic and wild carnivores [...]
Cristina E. Di Francesco +2 more
doaj +1 more source
Human Metapneumovirus Infection among Children, Bangladesh
Emerging Infectious Diseases, 2007 We confirmed circulation of human metapneumovirus (HMPV) among children with febrile and respiratory illness in an urban slum in Dhaka, Bangladesh, during active surveillance in 2001.
W. Abdullah Brooks +9 more
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The Evolutionary and Epidemiological Dynamics of the Paramyxoviridae [PDF]
Journal of Molecular Evolution, 2008 Paramyxoviruses are responsible for considerable disease burden in human and wildlife populations: measles and mumps continue to affect the health of children worldwide, while canine distemper virus causes serious morbidity and mortality in a wide range of mammalian species.
Laura W, Pomeroy +2 more
openaire +2 more sources
Genome-wide transposon mutagenesis of paramyxoviruses reveals constraints on genomic plasticity.
PLoS Pathogens, 2020 The antigenic and genomic stability of paramyxoviruses remains a mystery. Here, we evaluate the genetic plasticity of Sendai virus (SeV) and mumps virus (MuV), sialic acid-using paramyxoviruses that infect mammals from two Paramyxoviridae subfamilies ...
Satoshi Ikegame +8 more
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Вопросы вирусологии, 2022 Mumps is an infectious disease controlled by specific vaccine prophylaxis. To date, its social and epidemiological significance remains high. This is evidenced by the process of developing and implementing into the health care practices of many countries
T. S. Chekhlyaeva +4 more
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Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein
Nature Communications, 2023 Newcastle disease virus (NDV) belongs to Paramyxoviridae and encodes a large protein (L) and phosphoprotein (P) for viral RNA synthesis. Here the authors present cryo-EM structures of the L-P complex, and propose a model of how RNA initiation/elongation ...
Jingyuan Cong +8 more
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Immunopathogenesis of Nipah Virus Infection and Associated Immune Responses
Immuno, 2023 Pandemics in the last two centuries have been initiated by causal pathogens that include Severe Acute Coronavirus 2 (SARS-CoV-2) and Influenza (e.g., the H1N1 pandemic of 2009).
Brent Brown +7 more
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