Passaging of a Newcastle disease virus pigeon variant in chickens results in selection of viruses with mutations in the polymerase complex enhancing virus replication and virulence [PDF]
Some Newcastle disease virus (NDV) variants isolated from pigeons (pigeon paramyxovirus type 1; PPMV-1) do not show their full virulence potential for domestic chickens but may become virulent upon spread in these animals.
Dortmans, J.C.F.M. +3 more
core +2 more sources
Molecular Detection and Genetic Diversity of Measles and Parainfluenza Viruses Circulating in Humans in Bangladesh: A Cross-Sectional Study. [PDF]
ABSTRACT Background and Aims Among Paramyxoviruses (PMVs), measles virus (MeV) and human parainfluenza virus (HPIV) are major contributors to respiratory tract infections worldwide. Despite recurrent outbreaks of MeV and the significant health impact of HPIV, data on their molecular epidemiology and genetic diversity in Bangladesh remain scarce.
Choudhury SD +10 more
europepmc +2 more sources
Mumps is an infectious disease controlled by specific vaccine prophylaxis. To date, its social and epidemiological significance remains high. This is evidenced by the process of developing and implementing into the health care practices of many countries
T. S. Chekhlyaeva +4 more
doaj +1 more source
Envelope-receptor interactions in Nipah virus pathobiology. [PDF]
Nipah (NiV) and Hendra (HeV) viruses are members of the newly defined Henipavirus genus of the Paramyxoviridae. Nipah virus (NiV) is an emergent paramyxovirus that causes fatal encephalitis in up to 70% of infected patients, and there is increasing ...
Lee, Benhur
core +1 more source
Genome-wide transposon mutagenesis of paramyxoviruses reveals constraints on genomic plasticity.
The antigenic and genomic stability of paramyxoviruses remains a mystery. Here, we evaluate the genetic plasticity of Sendai virus (SeV) and mumps virus (MuV), sialic acid-using paramyxoviruses that infect mammals from two Paramyxoviridae subfamilies ...
Satoshi Ikegame +8 more
doaj +1 more source
Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein
Newcastle disease virus (NDV) belongs to Paramyxoviridae and encodes a large protein (L) and phosphoprotein (P) for viral RNA synthesis. Here the authors present cryo-EM structures of the L-P complex, and propose a model of how RNA initiation/elongation ...
Jingyuan Cong +8 more
doaj +1 more source
Mediterranean Fin Whales (Balaenoptera physalus) Threatened by Dolphin MorbilliVirus [PDF]
During 2011-2013, dolphin morbillivirus was molecularly identified in 4 stranded fin whales from the Mediterranean Sea. Nucleoprotein, phosphoprotein, and hemagglutinin gene sequences of the identified strain were highly homologous with those of a ...
BEFFAGNA, GIORGIA +11 more
core +3 more sources
Conformational Isomerization Involving Conserved Proline Residues Modulates Oligomerization of the NS1 Interferon Response Inhibitor from the Syncytial Respiratory Virus [PDF]
Interferon response suppression by the respiratory syncytial virus relies on two unique nonstructural proteins, NS1 and NS2, that interact with cellular partners through high-order complexes.
Alonso, Leonardo Gabriel +9 more
core +1 more source
Immunopathogenesis of Nipah Virus Infection and Associated Immune Responses
Pandemics in the last two centuries have been initiated by causal pathogens that include Severe Acute Coronavirus 2 (SARS-CoV-2) and Influenza (e.g., the H1N1 pandemic of 2009).
Brent Brown +7 more
doaj +1 more source
Sequence variation in the haemagglutinin-neuraminidase gene of human parainfluenza virus type 3 isolates in the UK [PDF]
The sequence variation in a 934 base-pair region of the gene encoding the haemagglutinin-neuraminidase of five human parainfluenza virus type 3 (HPIV3) isolates was determined together with that of a prototype UK strain. All of the clinical isolates were
K. R. Collins +6 more
core +1 more source

