Probable Human Infection with a Newly Described Virus in the Family Paramyxoviridae
After an apparently new virus in the family Paramyxoviridae was isolated from pigs in August 1997, an investigation was carried out to assess its risk for humans.
Kerry Chant +4 more
doaj +3 more sources
Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo. [PDF]
The early host response to pathogens is mediated by several distinct pattern recognition receptors. Cytoplasmic RNA helicases including RIG-I and MDA5 have been shown to respond to viral RNA by inducing interferon (IFN) production.
Leonid Gitlin +6 more
doaj +4 more sources
An Apparently New Virus (Family Paramyxoviridae) Infectious for Pigs, Humans, and Fruit Bats
We isolated an apparently new virus in the family Paramyxoviridae from stillborn piglets with deformities at a piggery in New South Wales, Australia. In 1997, the pregnancy rate and litter size at the piggery decreased markedly, while the proportion of ...
Adrian W. Philbey +8 more
doaj +3 more sources
Human IFIT1 inhibits mRNA translation of rubulaviruses but not other members of the Paramyxoviridae family [PDF]
This work was supported by The Welcome Trust (101788/Z/13/Z, 101792/Z/13/Z) and Medical research council grant (G1100110/1, MR/K024213/1).We have previously shown that IFIT1 is primarily responsible for the antiviral action of interferon (IFN) alpha/beta
Andrejeva, J. +7 more
core +7 more sources
INTRODUCTION Mumps is a viral infection of high social significance. National program Elimination of measles and rubella and achievement of a stable sporadic incidence of epidemic mumps in the Russian Federation (20212025) sets the aim of gradual ...
T. S. Rubalskaia +5 more
openalex +3 more sources
Investigation of T cell responses to Nipah virus by genome-wide antigen screening and conservation across Paramyxoviridae 4537 [PDF]
An important component of readiness against potential future viral pandemic is the broad study of adaptive immunity, to enable measurement of host responses and accelerate vaccine development and testing.
Alba Grifoni, Alessandro Sette
semanticscholar +3 more sources
Comparative Loss-of-Function Screens Reveal ABCE1 as an Essential Cellular Host Factor for Efficient Translation of Paramyxoviridae and Pneumoviridae [PDF]
The Paramyxoviridae and Pneumoviridae families include important human and animal pathogens. To identify common host factors, we performed genome-scale siRNA screens with wild-type-derived measles, mumps, and respiratory syncytial viruses in the same ...
Danielle E. Anderson +16 more
openalex +2 more sources
Henipavirus in Northern Short-Tailed Shrew, Alabama, USA [PDF]
RNA metagenomic analysis of tissues from 4 wild-caught northern short-tailed shrews in Alabama, USA, revealed a novel henipavirus (family Paramyxoviridae).
Rhys H. Parry +9 more
doaj +3 more sources

