Results 21 to 30 of about 11,878 (160)
Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein
Nature Communications, 2023 Newcastle disease virus (NDV) belongs to Paramyxoviridae and encodes a large protein (L) and phosphoprotein (P) for viral RNA synthesis. Here the authors present cryo-EM structures of the L-P complex, and propose a model of how RNA initiation/elongation ...
Jingyuan Cong +8 more
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Immunopathogenesis of Nipah Virus Infection and Associated Immune Responses
Immuno, 2023 Pandemics in the last two centuries have been initiated by causal pathogens that include Severe Acute Coronavirus 2 (SARS-CoV-2) and Influenza (e.g., the H1N1 pandemic of 2009).
Brent Brown +7 more
doaj +1 more source
Henipaviruses—A constant threat to livestock and humans
PLoS Neglected Tropical Diseases, 2022 In this review, we highlight the risk to livestock and humans from infections with henipaviruses, which belong to the virus family Paramyxoviridae. We provide a comprehensive overview of documented outbreaks of Nipah and Hendra virus infections affecting
Susann Kummer, Denise-Carina Kranz
doaj +2 more sources
Intervirology, 1978 Iit is proposed that the family paramyxovirdae shall comprise three genera: paramyxovirus, Morbillivirus, and Pneumovirus.
David W. Kingsbury +9 more
openaire +2 more sources
Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo. [PDF]
PLoS Pathogens, 2010 The early host response to pathogens is mediated by several distinct pattern recognition receptors. Cytoplasmic RNA helicases including RIG-I and MDA5 have been shown to respond to viral RNA by inducing interferon (IFN) production.
Leonid Gitlin +6 more
doaj +1 more source
Genetic Diversity and Geographic Spread of Henipaviruses
Emerging Infectious DiseasesHenipaviruses, such as Hendra and Nipah viruses, are major zoonotic pathogens that cause encephalitis and respiratory infections in humans and animals.
Yakhouba Kane +8 more
doaj +1 more source
Streamlined detection of Nipah virus antibodies using a split NanoLuc biosensor
Emerging Microbes and InfectionsNipah virus (NiV) is an emerging zoonotic RNA virus that can cause fatal respiratory and neurological diseases in animals and humans. Accurate NiV diagnostics and surveillance tools are crucial for the identification of acute and resolved infections and ...
Éric Bergeron +12 more
doaj +1 more source
Respiratory Tract Reinfections by the New Human Metapneumovirus in an Immunocompromised Child
Emerging Infectious Diseases, 2002 The human Metapneumovirus (HMPV), a new member of the Paramyxoviridae family, has been recently associated with respiratory tract infections in young children.
Gilles Pelletier +3 more
doaj +1 more source
Measles Virus Fusion Protein: Structure, Function and Inhibition
Viruses, 2016 Measles virus (MeV), a highly contagious member of the Paramyxoviridae family, causes measles in humans. The Paramyxoviridae family of negative single-stranded enveloped viruses includes several important human and animal pathogens, with MeV causing ...
Philippe Plattet +3 more
doaj +1 more source
iNew Medicine, EarlyView.This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng +3 more
wiley +1 more source