Results 51 to 60 of about 10,770 (147)

Carbohydrate‐Based Drug Discovery: Synthetic Strategies and Clinical Applications

Israel Journal of Chemistry, Volume 66, Issue 3, May 2026.
The picture depicts the molecules discussed in the review. On the left side, the general scaffold of sugars is shown. Next to it are four carbohydrate‐based molecules, including remdesivir, islatravir, empagliflozin, and Globo‐H. Remdesivir and islatravir contain a substituted ribose ring attached to a modified nucleobase.
Stephan Scheeff, Jemma Arakelyan, Billy Wai‐Lung Ng   +2 more
wiley   +1 more source

Probable human infection with a newly described virus in the family Paramyxoviridae. The NSW Expert Group.

Emerging infectious diseases, 1998
After an apparently new virus in the family Paramyxoviridae was isolated from pigs in August 1997, an investigation was carried out to assess its risk for humans. More than 250 persons with potential exposure to infected pigs were tested serologically. Two piggery workers with intense occupational exposure had high convalescent-phase antibody titers to
K, Chant, R, Chan, M, Smith, D E, Dwyer, P, Kirkland   +4 more
openaire   +1 more source

Parainfluenza virus as a cause of acute respiratory infection in hospitalized children

Brazilian Journal of Infectious Diseases, 2015
Background: Human parainfluenza viruses account for a significant proportion of lower respiratory tract infections in children. Objective: To assess the prevalence of Human parainfluenza viruses as a cause of acute respiratory infection and to compare ...
Rogério Pecchini, Eitan Naaman Berezin, Maria Cândida Souza, Lourdes de Andrade Vaz-de-Lima, Neuza Sato, Maristela Salgado, Mirthes Ueda, Saulo Duarte Passos, Raphael Rangel, Ana Catebelota   +9 more
doaj   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, Volume 46, Issue 3, Page 672-712, May 2026.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

Nipah Virus - Agent of Infectious Dangerous Disease

Проблемы особо опасных инфекций, 2015
The review provides the information on etiology, epidemiology, clinical features and prevention of a little-known viral encephalitis Nipah. Given is the characteristics of the pathogen and its ecology.
E. P. Lukin
doaj   +1 more source

Evaluation of Selected Brain Damage Biomarkers in the Determination of Brain Damage in Dogs With Neurological Distemper

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
In this study, a significant increase in serum NSE, GFAP, CK‐B, IgM and IgM concentrations was determined in dogs with nervous distemper. It was shown that NSE, GFAP and CK‐B biomarkers have a useful and reliable diagnostic value in determining brain damage in dogs with nervous distemper .
Muhammed Mustafa Kapar, Mahmut Ok, Oğuzhan Avcı   +2 more
wiley   +1 more source

Genome-wide siRNA Screening at Biosafety Level 4 Reveals a Crucial Role for Fibrillarin in Henipavirus Infection.

PLoS Pathogens, 2016
Hendra and Nipah viruses (genus Henipavirus, family Paramyxoviridae) are highly pathogenic bat-borne viruses. The need for high biocontainment when studying henipaviruses has hindered the development of therapeutics and knowledge of the viral infection ...
Celine Deffrasnes, Glenn A Marsh, Chwan Hong Foo, Christina L Rootes, Cathryn M Gould, Julian Grusovin, Paul Monaghan, Michael K Lo, S Mark Tompkins, Timothy E Adams, John W Lowenthal, Kaylene J Simpson, Cameron R Stewart, Andrew G D Bean, Lin-Fa Wang   +14 more
doaj   +1 more source

Effect of Respiratory Syncytial Virus on the Global Burden of Lower Respiratory Infections: Lessons From the Global Burden of Disease Study 1990–2021

Immunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
ABSTRACT Background Respiratory syncytial virus (RSV) is a major cause of lower respiratory infections (LRIs), especially in children, the elderly, and immunocompromised individuals. Methods Using GBD 1990–2021 data, we analyzed global RSV‐related LRI deaths and DALYs. Trends were assessed via age‐standardized rates and joinpoint regression.
Jiafen Zhao, Tao Zhou, Cheng Jiang, Feng Peng   +3 more
wiley   +1 more source

Respiratory Syncytial Virus and Cellular Stress Responses: Impact on Replication and Physiopathology

Viruses, 2016
Human respiratory syncytial virus (RSV), a member of the Paramyxoviridae family, is a major cause of severe acute lower respiratory tract infection in infants, elderly and immunocompromised adults.
Sandra L. Cervantes-Ortiz, Natalia Zamorano Cuervo, Nathalie Grandvaux   +2 more
doaj   +1 more source

Developmental influence on respiratory epithelia to Paramyxoviridae infection, beta-defensin expression and adenoviral delivery of a beta-defensin gene

, 2018
Preterm birth is an increasing statistic among American mothers. Young infants are at increased risk for developing severe manifestations of Paramyxoviral infection, including respiratory syncytial virus (RSV) and parainfluenza virus-3 (PIV3).
openaire   +3 more sources