mSphere, 2020 Between 2015 and 2017, routine molecular surveillance in the United States detected multiple mumps viruses (MuVs) with mutations in the small hydrophobic (SH) gene compared to a reference virus of the same genotype.
Rita Czakó Stinnett +7 more
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Sendai Virus-Vectored Vaccines That Express Envelope Glycoproteins of Respiratory Viruses
Viruses, 2021 Human respiratory syncytial virus (HRSV), human metapneumovirus (HMPV), and human parainfluenza viruses (HPIVs) are leading causes of respiratory disease in young children, the elderly, and individuals of all ages with immunosuppression.
Charles J. Russell, Julia L. Hurwitz
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Paramyxovirus V proteins interact with the RNA helicase LGP2 to inhibit RIG-I-dependent interferon induction [PDF]
, 2012 This work was supported by the Wellcome Trust (grant AL087751/B)RIG-I and mda-5 are activated by viral RNA and stimulate type I interferon production. Laboratory of genetics and physiology 2 (LGP2) shares homology with RIG-I and mda-5 but lacks the CARD ...
Childs, Kay +2 more
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Structural and mechanistic studies of measles virus illuminate paramyxovirus entry.
PLoS Pathogens, 2011 Measles virus (MeV), a member of the paramyxovirus family of enveloped RNA viruses and one of the most infectious viral pathogens identified, accounts for major pediatric morbidity and mortality worldwide although coordinated efforts to achieve global ...
Richard K Plemper +2 more
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Parenteral vaccination of mammalian livestock with Newcastle disease virus-based vector vaccines offers optimal efficacy and safety [PDF]
, 2011 Newcastle disease virus (NDV) is an avian virus that is being evaluated as a vaccine vector for the delivery of foreign genes in mammals. The use of NDV as a vaccine vector in these species offers two major advantages.
Antonis, A.F.G. +3 more
core +2 more sources
The R2TP complex regulates paramyxovirus RNA synthesis.
PLoS Pathogens, 2019 The regulation of paramyxovirus RNA synthesis by host proteins is poorly understood. Here, we identified a novel regulation mechanism of paramyxovirus RNA synthesis by the Hsp90 co-chaperone R2TP complex.
Hiroshi Katoh +9 more
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Investigation of histopathological alteration of paramyxovirus-1 in naturally infected racing pigeons [PDF]
Iraqi Journal of Veterinary SciencesThe current study aimed to investigate the infection of racing pigeons with paramyxovirus-1(PMV-1) based on clinical signs of histological and histochemical changes, which increase the mortality rate in flocks called pigeons paramyxovirus.
Ayman A. Al-Alhially +2 more
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Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation. [PDF]
, 2017 Nipah virus is an emergent paramyxovirus that causes deadly encephalitis and respiratory infections in humans. Two glycoproteins coordinate the infection of host cells, an attachment protein (G), which binds to cell surface receptors, and a fusion (F ...
Jardetzky, Theodore S +9 more
core +2 more sources
High prevalence of Sarcocystis calchasi in racing pigeon flocks in Germany [PDF]
, 2019 The apicomplexan parasite Sarcocystis calchasi (Coccidia: Eimeriorina: Sarcocystidae) is the causative agent of Pigeon Protozoal Encephalitis (PPE) and infects birds of the orders Columbiformes, Piciformes and Psittaciformes.
Failing, Klaus +4 more
core +1 more source
Should Mumps Be Higher Up on the Public Health Agenda in India? A Concern for Global Health Security
Medical Sciences, 2018 Mumps is a public health problem on a global scale caused by mumps virus, a member of family paramyxoviridae. An effective form of vaccination exists and is incorporated into routine immunization schedules in over 100 countries, usually in the form of ...
Syed Manzoor Kadri +4 more
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