Results 31 to 40 of about 15,173 (180)
, 2013 The family Paramyxoviridae consists of a group of large, enveloped, negative-sense, single-stranded RNA viruses and contains many important human and animal pathogens. Molecular and biochemical characterization over the past decade has revealed an extraordinary breadth of biological diversity among this family of viruses.
Katharine N, Bossart +2 more
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Fusogenic Variants of a Noncytopathic Paramyxovirus [PDF]
Journal of Virology, 2007 ABSTRACTSER virus is a type 5 parainfluenza virus that does not exhibit syncytium formation, in contrast to most other paramyxoviruses. This property has been attributed, at least in part, to the presence of an extension of the cytoplasmic tail (CT) of the SER F protein, as truncations or mutations of this region resulted in enhanced fusion.
Shaguna, Seth +3 more
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Should Mumps Be Higher Up on the Public Health Agenda in India? A Concern for Global Health Security
Medical Sciences, 2018 Mumps is a public health problem on a global scale caused by mumps virus, a member of family paramyxoviridae. An effective form of vaccination exists and is incorporated into routine immunization schedules in over 100 countries, usually in the form of ...
Syed Manzoor Kadri +4 more
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Structure and organization of paramyxovirus particles [PDF]
Current Opinion in Virology, 2017 The paramyxovirus family comprises major human and animal pathogens such as measles virus (MeV), mumps virus (MuV), the parainfluenzaviruses, Newcastle disease virus (NDV), and the highly pathogenic zoonotic hendra (HeV) and nipah (NiV) viruses. Paramyxovirus particles are pleomorphic, with a lipid envelope, nonsegmented RNA genomes of negative ...
Robert M, Cox, Richard K, Plemper
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Angiomotin-Like 1 Links Paramyxovirus M Proteins to NEDD4 Family Ubiquitin Ligases
Viruses, 2019 To define the links between paramyxovirus budding and cellular ESCRT machinery, we previously identified angiomotin-like 1 (AMOTL1) in a screen for host factors that bind to the matrix (M) protein of parainfluenza virus 5 (PIV5).
Greeshma Ray +2 more
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Reengineering paramyxovirus tropism
Virology, 2004 Receptor specificity is a critical determinant of viral tropism, but the capacity of viruses to switch to alternative receptors has not been extensively studied. Here, we engineered the attachment protein of an attenuated measles virus and generated truly retargeted viruses that are blind to the native receptors CD46 and SLAM, but which propagate ...
Hadac, Elizabeth M. +3 more
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Diversity and Evolution of Viral Pathogen Community in Cave Nectar Bats (Eonycteris spelaea)
Viruses, 2019 Bats are unique mammals, exhibit distinctive life history traits and have unique immunological approaches to suppression of viral diseases upon infection.
Ian H Mendenhall +7 more
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The structural basis of paramyxovirus invasion [PDF]
Trends in Microbiology, 2006 To deliver their genetic material into host cells, enveloped viruses have surface glycoproteins that actively cause the fusion of the viral and cellular membranes. Recently determined X-ray crystal structures of the paramyxovirus fusion (F) protein in its pre-fusion and post-fusion conformations reveal the dramatic structural transformation that this ...
Russell, Charles J., Luque, Laura E.
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Human metapneumovirus Induces Reorganization of the Actin Cytoskeleton for Direct Cell-to-Cell Spread. [PDF]
PLoS Pathogens, 2016 Paramyxovirus spread generally involves assembly of individual viral particles which then infect target cells. We show that infection of human bronchial airway cells with human metapneumovirus (HMPV), a recently identified paramyxovirus which causes ...
Farah El Najjar +6 more
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Glycoprotein Interactions in Paramyxovirus Fusion [PDF]
Future Virology, 2009 The Paramyxoviridae are enveloped, negative-stranded RNA viruses, some of which recognize sialic acid-containing receptors, while others recognize specific proteinaceous receptors. The major cytopathic effect of paramyxovirus infection is membrane fusion-induced syncytium formation.
Ronald M, Iorio +2 more
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