Results 51 to 60 of about 18,630 (214)

Bacterial sialidases subvert the complement system through desialylation

Protein Science, Volume 35, Issue 11, November 2026.
Abstract Bacterial sialidases (neuraminidases) are widely studied virulence factors, yet their impact on the complement system, a central component of innate immunity, remains poorly understood. Here, we investigate the effects of six sialidases from five human pathogens, including Bacteroides fragilis, Clostridium perfringens, Tannerella forsythia ...
Kurni Kurniyati, Nicholas D. Clark, Qin Fu, Sheng Zhang, Weigang Qiu, Michael G. Malkowski, Chunhao Li   +6 more
wiley   +1 more source

The structural basis of paramyxovirus invasion [PDF]

Trends in Microbiology, 2006
To deliver their genetic material into host cells, enveloped viruses have surface glycoproteins that actively cause the fusion of the viral and cellular membranes. Recently determined X-ray crystal structures of the paramyxovirus fusion (F) protein in its pre-fusion and post-fusion conformations reveal the dramatic structural transformation that this ...
Russell, Charles J., Luque, Laura E.
openaire   +2 more sources

Viral evolution identifies a regulatory interface between paramyxovirus polymerase complex and nucleocapsid that controls replication dynamics

, 2020
International audienceA protein interface between paramyxovirus polymerase and nucleocapsid is involved in regulating viral replication ...
Richard K. Plemper, Robert M. Cox, Julien Sourimant, Sourimant, Julien, Thakkar, Vidhi, Vidhi D. Thakkar, Plemper, Richard, Cox, Robert   +7 more
core   +1 more source

Vaccine Quality Is a Key Factor to Determine Thermal Stability of Commercial Newcastle Disease (ND)Vaccines

Vaccines, 2021
Vaccination against Newcastle disease (ND), a devastating viral disease of chickens, is often hampered by thermal inactivation of the live vaccines, in particular in tropical and hot climate conditions.
Nabila Osman, Danny Goovaerts, Serageldeen Sultan, Jeremy Salt, Christian Grund   +4 more
doaj   +1 more source

A Rapid Method to Rank Proteins of Widely Varying Stability: Application to Paramyxovirus Foot Domains

Current Protocols, Volume 6, Issue 10, October 2026.
Abstract The foot domains of polymerases from the Paramyxoviridae family mediate attachment of the viral polymerases to their nucleocapsid templates during viral RNA synthesis. Detailed structural and biophysical characterization of these foot domains reveals that they share a common structure, but when not bound to the nucleocapsid they may exist as ...
Andrew C. Hausrath, Richard L. Kingston, Megan M. McEvoy   +2 more
wiley   +1 more source

Diagnosis and Management of Infectious Encephalitis in Adults: Guidelines From the European Academy of Neurology and European Society of Clinical Microbiology and Infectious Diseases

European Journal of Neurology, Volume 33, Issue 10, October 2026.
ABSTRACT Background Encephalitis is difficult to diagnose and manage, posing a challenge to clinicians. Since the last European guidelines were published in 2010, novel causes have emerged, diagnostic processes have evolved and treatments assessed which need to be reflected in updated guidelines.
Julia Granerod, Johann Sellner, Jean‐Paul Stahl, Sylviane Defres, Alexandra Mailles, Erich Schmutzhard, Elisabeth Aurelius, Thomas Whitfield, Luca Massacesi, Maarten J. Titulaer, Pille Taba, Benedict D. Michael, Tehmina Bharucha, Lance Turtle, Brendan Sargent, Arina Tamborska, Jonathan Cattrall, Yun Huang, Eva Maria Hodel, Suzannah Lant, Glynn Webb, Rajish S. K. Shil, Shalley Dhar, Diederik van de Beek, Marie Studahl, Matthijs C. Brouwer, Uta Meyding‐Lamade, Ava Easton, Bhagteshwar Singh, Tom Solomon   +29 more
wiley   +1 more source

Structure and organization of paramyxovirus particles [PDF]

Current Opinion in Virology, 2017
The paramyxovirus family comprises major human and animal pathogens such as measles virus (MeV), mumps virus (MuV), the parainfluenzaviruses, Newcastle disease virus (NDV), and the highly pathogenic zoonotic hendra (HeV) and nipah (NiV) viruses. Paramyxovirus particles are pleomorphic, with a lipid envelope, nonsegmented RNA genomes of negative ...
Robert M, Cox, Richard K, Plemper
openaire   +2 more sources

Cysteine Redox State Governs the Condensation Pathway of Hendra Virus W Protein and Differentially Impacts Type I IFN and NF‐κB Signaling

Advanced Science, Volume 13, Issue 52, 18 September 2026.
The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud, Alexandre Lalande, Giulia Pesce, Auriane Bouchet, Carole Meunier, Christophe Bignon, Denis Ptchelkine, Yu Gu, Eva Ogire, Pierre‐Yves Lozach, Denis Gerlier, Cyrille Mathieu, Sonia Longhi   +12 more
wiley   +1 more source

Molecular Epidemiology of Peste des Petits Ruminants Virus Circulating in Fat‐Tailed Sheep in Bangladesh

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study reports the molecular detection and genetic characterization of peste des petits ruminants virus in fat‐tailed sheep in Bangladesh. Phylogenetic analysis reveals transboundary lineage circulation, highlighting silent virus movement during high‐risk livestock trading periods and the need for strengthened regional surveillance.
Md. Arif Khan, Pronesh Dutta, Md. Kaisar Rahman, Abdullah‐Al Mamun, Jade K. Forwood, Shariful Islam, Ariful Islam   +6 more
wiley   +1 more source

Lineage diversification of pigeon paramyxovirus effect re-emergence potential in chickens [PDF]

, 2014
Genotype VI-paramyxovirus (GVI-PMV1) is a major cause of epidemic Newcastle-like disease in Columbiformes. This genotype of avian paramyxovirus type 1 has diversified rapidly since its introduction into the US in 1982 resulting in two extant lineages ...
Yee, Ling Chong, Oekyung, Kim, Ross, Mary   +2 more
core   +2 more sources