Results 71 to 80 of about 23,460 (223)

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

Host Retromer Protein Sorting Nexin 2 Interacts with Human Respiratory Syncytial Virus Structural Proteins and is Required for Efficient Viral Production

mBio, 2020
Human respiratory syncytial virus (HRSV) envelope glycoproteins traffic to assembly sites through the secretory pathway, while nonglycosylated proteins M and N are present in HRSV inclusion bodies but must reach the plasma membrane, where HRSV assembly ...
Ricardo S. Cardoso, Lucas Alves Tavares, Bruna Lais S. Jesus, Miria F. Criado, Andreia Nogueira de Carvalho, Juliano de Paula Souza, Sukhmani Bedi, Marcos Michel de Souza, Maria Lucia Silva, Guilherme Pauperio Lanfredi, Brenda Cristina Vitti, Orlando Bonito Scudero, Vitor Marcel Faça, Akira Ono, Armando M. Ventura, Luis Lamberti P. daSilva, Eurico Arruda   +16 more
doaj   +1 more source

Isolation and Molecular Detection of Newcastle Disease Virus From Outbreak Cases in Selected Areas of Northern and Western Oromia, Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
ABSTRACT Newcastle disease (ND) is a commonly fatal viral disease that has been reported to affect a wide range of avian hosts, irrespective of their age and sex. It is reported to be a major constraint to the development, survival, and productivity of poultry in Ethiopia.
Yobsan Tamiru, Abde Aliyi, Demesa Negessu   +2 more
wiley   +1 more source

A Single Point Mutation in the Mumps V Protein Alters Targeting of the Cellular STAT Pathways Resulting in Virus Attenuation

Viruses, 2019
Mumps virus (MuV) is a neurotropic non-segmented, negative-stranded, enveloped RNA virus in the Paramyxovirus family. The 15.4 kb genome encodes seven genes, including the V/P, which encodes, among other proteins, the V protein.
Tahir Malik, Laurie Ngo, Trent Bosma, Steven Rubin   +3 more
doaj   +1 more source

Interaction of mumps virus V protein variants with STAT1-STAT2 heterodimer: experimental and theoretical studies [PDF]

, 2010
Background Mumps virus V protein has the ability to inhibit the interferon-mediated antiviral response by inducing degradation of STAT proteins. Two virus variants purified from Urabe AM9 mumps virus vaccine differ in their replication and transcription ...
Nora H Rosas-Murrieta, Irma Herrera-Camacho, Helen Palma-Ocampo, Gerardo Santos-López, Julio Reyes-Leyva   +4 more
core   +1 more source

Efficacy of a Combined Natural Extract of Turmeric (Curcuma longa) and Liquorice (Glycyrrhiza uralensis) Against Viral Haemorrhagic Septicaemia Virus in Olive Flounders (Paralichthys olivaceus)

Journal of Fish Diseases, Volume 49, Issue 1, January 2026.
ABSTRACT Viral haemorrhagic septicaemia virus (VHSV) causes a high mortality rate in cultured olive flounder, and effective treatment for VHSV infection is urgently required. Turmeric (Curcuma longa ) and liquorice (Glycyrrhiza uralensis) are well‐known medicinal plants with a variety of biological activities. Turmeric and liquorice extract combination
Su‐Mi Shin, Walimuni Randika Harshan Mendis, So Young Kang, Hyung Jae Jeong, Taeho Kim, Sung‐Ju Jung   +5 more
wiley   +1 more source

Respiratory Tract Reinfections by the New Human Metapneumovirus in an Immunocompromised Child

Emerging Infectious Diseases, 2002
The human Metapneumovirus (HMPV), a new member of the Paramyxoviridae family, has been recently associated with respiratory tract infections in young children.
Gilles Pelletier, Pierre Déry, Yacine Abed, Guy Boivin   +3 more
doaj   +1 more source

Medicinal Plants and Lead Phytomolecules as Immunomodulators: An Updated Review

BioMed Research International, Volume 2026, Issue 1, 2026.
All therapeutic interventions aimed at modulating the immune response to pathogens, self‐antigens, carcinogens, or xenogeneic antigens are referred to as immunomodulation, which either prevents hyperactivation or restores the appropriate response of the immune system.
Gurdeep Singh, Vikas Sharma, Blessing Nnenna Udeh, Baisakhi Banerjee   +3 more
wiley   +1 more source

Novel Paramyxoviruses in Bats from Sub-Saharan Africa, 2007–2012

Emerging Infectious Diseases, 2015
As part of a larger survey for detection of pathogens among wildlife in sub-Saharan Africa conducted during 2007–2012, multiple diverse paramyxovirus sequences were detected in renal tissues of bats.
Marinda Mortlock, Ivan V. Kuzmin, Jacqueline Weyer, Amy T. Gilbert, Bernard Agwanda, Charles E. Rupprecht, Louis H. Nel, Teresa Kearney, Jean Malekani, Wanda Markotter   +9 more
doaj   +1 more source

Defective interfering virus protects elderly mice from influenza [PDF]

, 2011
Background: We have identified and characterised a defective-interfering (DI) influenza A virus particles containing a highly deleted segment 1 RNA that has broad-spectrum antiviral activity.
Scott, P. D. (Paul D.), Meng, Bo, Marriott, Anthony C., Easton, A. J. (Andrew J.), Dimmock, N. J.   +4 more
core   +3 more sources