Results 61 to 70 of about 23,460 (223)

Highly Potent Host-Specific Small-Molecule Inhibitor of Paramyxovirus and Pneumovirus Replication with High Resistance Barrier

mBio, 2021
Multiple enveloped RNA viruses of the family Paramyxoviridae and Pneumoviridae, like measles virus (MeV), Nipah virus (NiV), canine distemper virus (CDV), or respiratory syncytial virus (RSV), are of high clinical relevance.
Neeta Shrestha, Flavio Max Gall, Cyrille Mathieu, Melanie Michaela Hierweger, Melanie Brügger, Marco P. Alves, Jonathan Vesin, Damiano Banfi, David Kalbermatter, Branka Horvat, Marc Chambon, Gerardo Turcatti, Dimitrios Fotiadis, Rainer Riedl, Philippe Plattet   +14 more
doaj   +1 more source

A Novel Jeilongvirus from Florida, USA, Has a Broad Host Cell Tropism Including Human and Non-Human Primate Cells

Pathogens
A novel jeilongvirus was identified through next-generation sequencing in cell cultures inoculated with spleen and kidney extracts. The spleen and kidney were obtained from a Peromyscus gossypinus rodent (cotton mouse) found dead in the city of ...
Emily DeRuyter, Kuttichantran Subramaniam, Samantha M. Wisely, J. Glenn Morris, John A. Lednicky   +4 more
doaj   +1 more source

Co-Circulation and Excretion Dynamics of Diverse Rubula- and Related Viruses in Egyptian Rousette Bats from South Africa

Viruses, 2019
The Egyptian rousette bat (Rousettus aegyptiacus) has previously been implicated as the natural host of a zoonotic rubulavirus; however, its association with rubulaviruses has been studied to a limited extent.
Marinda Mortlock, Muriel Dietrich, Jacqueline Weyer, Janusz T. Paweska, Wanda Markotter   +4 more
doaj   +1 more source

Cohorts of immature Pteropus bats show interannual variation in Hendra virus serology

Journal of Animal Ecology, Volume 95, Issue 3, Page 521-537, March 2026.
Pteropus bat with offspring, photo taken by Manuel Ruiz‐Aravena. Abstract Understanding the drivers of seasonal disease outbreaks remains a fundamental challenge in disease ecology. Periodic outbreaks can be driven by several seasonally varying factors, including pulses of susceptible individuals through births, changes in host behaviour and social ...
Daniel E. Crowley, Caylee A. Falvo, Chris K. Grant, Benny Borremans, Tamika J. Lunn, Manuel Ruiz‐Aravena, Evelyn Benson, Clifton D. McKee, Daniel J. Becker, Devin N. Jones, Trenton Bushmaker, Y. Tina Yu, Michelle Michie, Adrienne S. Dale, Lianying Yan, Spencer L. Sterling, Christopher C. Broder, Laura B. Goodman, Rasa Petraityte‐Burneikiene, Eric D. Laing, Ina L. Smith, Vincent J. Munster, Agnieszka Rynda‐Apple, Alison J. Peel, Raina Plowright   +24 more
wiley   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, Volume 15, Issue 6, 9 February 2026.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Histopathologic and Immunohistochemical Evaluation of Induced Lesions, Tissue Tropism and Host Responses following Experimental Infection of Egyptian Rousette Bats (Rousettus aegyptiacus) with the Zoonotic Paramyxovirus, Sosuga Virus

Viruses, 2022
Ecological and experimental infection studies have identified Egyptian rousette bats (ERBs; Rousettus aegyptiacus: family Pteropodidae) as a reservoir host for the zoonotic rubula-like paramyxovirus Sosuga virus (SOSV). A serial sacrifice study of colony-
Shannon G. M. Kirejczyk, Brian R. Amman, Amy J. Schuh, Tara K. Sealy, César G. Albariño, Jian Zhang, Corrie C. Brown, Jonathan S. Towner   +7 more
doaj   +1 more source

The Prefusogenic Intermediate of HIV-1 gp41 Contains Exposed C-peptide Regions [PDF]

, 2003
The human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein is composed of a complex between the surface subunit gp120, which binds to cellular receptors, and the transmembrane subunit gp41.
Chan, David C., Koshiba, Takumi
core  

Orthomyxo-, paramyxo- and flavivirus infections in wild waterfowl in Finland [PDF]

, 2008
Background Screening wild birds for viral pathogens has become increasingly important. We tested a screening approach based on blood and cloacal and tracheal swabs collected by hunters to study the prevalence of influenza A, paramyxo-, flavi-, and ...
Lindh, Erika, Huovilainen, Anita, Ratti, Osmo, Ek-Kommonen, Christine, Sironen, Tarja, Huhtamo, Eili, Poysa, Hannu, Vaheri, Antti, Vapalahti, Olli   +8 more
core   +2 more sources

Global Epidemiology and Disease Burden of Human Parainfluenza Virus in Adults: A Systematic Review

Reviews in Medical Virology, Volume 36, Issue 1, January 2026.
ABSTRACT Parainfluenza virus (PIV) is a common cause of respiratory illness in children and immunocompromised adults, but little is known about its epidemiology or disease burden in the general adult population. This review evaluates published global epidemiological and disease burden for PIV in adults, including high‐risk patients (immunocompromised ...
Oliver Martyn, Clemens Vlasich, Veronika Khariv, Lauren C. Boudewyn, Peter J. M. Openshaw, Rolf Kramer   +5 more
wiley   +1 more source

The nanoscale organization of the Nipah virus fusion protein informs new membrane fusion mechanisms

eLife
Paramyxovirus membrane fusion requires an attachment protein for receptor binding and a fusion protein for membrane fusion triggering. Nipah virus (NiV) attachment protein (G) binds to ephrinB2 or -B3 receptors, and fusion protein (F) mediates membrane ...
Qian Wang, Jinxin Liu, Yuhang Luo, Vicky Kliemke, Giuliana Leonarda Matta, Jingjing Wang, Qian Liu   +6 more
doaj   +1 more source