Results 81 to 90 of about 15,173 (180)

Phylogenetic analysis of the promoter element 2 of paramyxo- and filoviruses

Microbiology Spectrum
Paramyxo- and filovirus genomes are equipped with bipartite promoters at their 3' ends to initiate RNA synthesis. The two elements, the primary promoter element 1 (PE1) and the secondary promoter element 2 (PE2), are separated by a spacer region that ...
Shoichi Ashida, Shohei Kojima, Takashi Okura, Fumihiro Kato, Wakako Furuyama, Shuzo Urata, Yusuke Matsumoto   +6 more
doaj   +1 more source

Alston Virus, a Novel Paramyxovirus Isolated from Bats Causes Upper Respiratory Tract Infection in Experimentally Challenged Ferrets

Viruses, 2018
Multiple viruses with zoonotic potential have been isolated from bats globally. Here we describe the isolation and characterization of a novel paramyxovirus, Alston virus (AlsPV), isolated from urine collected from an Australian pteropid bat colony in ...
Rebecca I. Johnson, Mary Tachedjian, Brenton Rowe, Bronwyn A. Clayton, Rachel Layton, Jemma Bergfeld, Lin-Fa Wang, Glenn A. Marsh   +7 more
doaj   +1 more source

Efficient and Robust Paramyxoviridae Reverse Genetics Systems

mSphere, 2017
The notoriously low efficiency of Paramyxoviridae reverse genetics systems has posed a limiting barrier to the study of viruses in this family. Previous approaches to reverse genetics have utilized a wide variety of techniques to overcome the technical ...
Shannon M. Beaty, Arnold Park, Sohui T. Won, Patrick Hong, Michael Lyons, Frederic Vigant, Alexander N. Freiberg, Benjamin R. tenOever, W. Paul Duprex, Benhur Lee   +9 more
doaj   +1 more source

Genotype I Newcastle Disease Virus, Isolated from Wild Duck, Can Protect Chickens Against Newcastle Disease Caused by Genotype VII

Pathogens
Newcastle disease viruses (NDVs) circulating among wild birds and poultry may differ in virulence. Some NDVs cause devastating outbreaks in chickens. The NDV/duck/Moscow/3639/2008 (d3639) strain was isolated from a wild duck.
Elizaveta Boravleva, Anastasia Treshchalina, Daria Gordeeva, Alexandra Gambaryan, Alla Belyakova, Irina Gafarova, Alexey Prilipov, Galina Sadykova, Simone Adams, Tatiana Timofeeva, Natalia Lomakina   +10 more
doaj   +1 more source

Inhibiting Human Parainfluenza Virus Infection by Preactivating the Cell Entry Mechanism

mBio, 2019
Paramyxoviruses, specifically, the childhood pathogen human parainfluenza virus type 3, are internalized into host cells following fusion between the viral and target cell membranes.
S. F. Bottom-Tanzer, K. Rybkina, J. N. Bell, C. A. Alabi, C. Mathieu, M. Lu, S. Biswas, M. Vasquez, M. Porotto, J. A. Melero, V. Más, A. Moscona   +11 more
doaj   +1 more source

Amino acid changes accumulated in the fusion protein allow neuropathogenic measles viruses to use a broad repertoire of host factors for cell fusion triggering

Journal of Virology
Measles virus (MeV), an enveloped RNA virus belonging to the genus Morbillivirus of the family Paramyxoviridae, is the causative agent of measles, an acute febrile illness with skin rash. MeV has two types of envelope glycoproteins: the hemagglutinin (H)
Yuichi Hirai, Ryuichi Takemoto, Yusuke Yanagi, Yuta Shirogane   +3 more
doaj   +1 more source

A New Genotype of Feline Morbillivirus Infects Primary Cells of the Lung, Kidney, Brain and Peripheral Blood

Viruses, 2019
Paramyxoviruses comprise a large number of diverse viruses which in part give rise to severe diseases in affected hosts. A new genotype of feline morbillivirus, tentatively named feline morbillivirus genotype 2 (FeMV-GT2), was isolated from urine of cats
Michael Sieg, Johannes Busch, Maria Eschke, Denny Böttcher, Kristin Heenemann, Annett Vahlenkamp, Anja Reinert, Johannes Seeger, Romy Heilmann, Kira Scheffler, Thomas W. Vahlenkamp   +10 more
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Glycosylation as a strategic mechanism for measles virus and mumps virus immune evasion

Frontiers in Immunology
Glycosylation of viral surface proteins by host cell factors is one strategy paramyxoviruses employ to evade the host’s immune system during infection. Viral glycosylation thus has the potential for innate and adaptive immune modulation.
Catalina Galvan, Inna G. Ovsyannikova, Richard B. Kennedy   +2 more
doaj   +1 more source

Reactivation of anaconda paramyxovirus infection after 13 years of latency

EMI: Animal & Environment
From July 2011 to June 2012, 31 green anaconda (Eunectes murinus) juveniles, progeny of a female anaconda purchased from Japan and added to the Ocean Park, Hong Kong collection in May 2011, died over a 12-month period.
Paolo Martelli, Jade L. L. Teng, Mei-Hui Chen, Hoklai Ho, Foo Khong Lee, Tsz Tuen Li, Andrew M. D. Ferguson, Susanna K. P. Lau, Patrick C. Y. Woo   +8 more
doaj   +1 more source

Henipavirus Mediated Membrane Fusion, Virus Entry and Targeted Therapeutics

Viruses, 2012
The Paramyxoviridae genus Henipavirus is presently represented by the type species Hendra and Nipah viruses which are both recently emerged zoonotic viral pathogens responsible for repeated outbreaks associated with high morbidity and mortality in ...
Dimitar B. Nikolov, Christopher C. Broder, Deborah L. Steffen, Kai Xu   +3 more
doaj   +1 more source