Results 11 to 20 of about 18,630 (214)
The Paramyxovirus Polymerase Complex as a Target for Next-Generation Anti-Paramyxovirus Therapeutics [PDF]
Frontiers in Microbiology, 2015 The paramyxovirus family includes major human and animal pathogens, including measles virus, mumps virus, and human respiratory syncytial virus (RSV), as well as the emerging zoonotic Hendra and Nipah viruses.
Richard K Plemper, Robert eCox
doaj +5 more sources
Envelope Protein Dynamics in Paramyxovirus Entry [PDF]
mBio, 2013 Paramyxoviruses include major pathogens with significant global health and economic impact. This large family of enveloped RNA viruses infects cells by employing two surface glycoproteins that tightly cooperate to fuse their lipid envelopes with the ...
Philippe Plattet, Richard K. Plemper
doaj +9 more sources
, 2020 La famiglia dei Paramyxovirus comprende importanti patogeni, tra i quali i virus che causano la parotite, il morbillo e il virus respiratorio sinciziale. Sono costituiti da un genoma a RNA singolo filamento a polarità€ negativa racchiuso in un nucleocapside a simmetria elicoidale a sua volta circondato da un pericapside pleiomorfo. Sono responsabili di
Cristina Lagatolla
core +4 more sources
The R2TP complex regulates paramyxovirus RNA synthesis.
PLoS Pathogens, 2019 The regulation of paramyxovirus RNA synthesis by host proteins is poorly understood. Here, we identified a novel regulation mechanism of paramyxovirus RNA synthesis by the Hsp90 co-chaperone R2TP complex.
Hiroshi Katoh +9 more
doaj +2 more sources
Investigation of histopathological alteration of paramyxovirus-1 in naturally infected racing pigeons [PDF]
Iraqi Journal of Veterinary SciencesThe current study aimed to investigate the infection of racing pigeons with paramyxovirus-1(PMV-1) based on clinical signs of histological and histochemical changes, which increase the mortality rate in flocks called pigeons paramyxovirus.
Ayman A. Al-Alhially +2 more
doaj +3 more sources
Structural and mechanistic studies of measles virus illuminate paramyxovirus entry.
PLoS Pathogens, 2011 Measles virus (MeV), a member of the paramyxovirus family of enveloped RNA viruses and one of the most infectious viral pathogens identified, accounts for major pediatric morbidity and mortality worldwide although coordinated efforts to achieve global ...
Richard K Plemper +2 more
doaj +2 more sources
mBio, 2023 Increased viral surveillance has led to the isolation and identification of numerous uncharacterized paramyxoviruses, rapidly expanding our understanding of paramyxoviral diversity beyond the bounds of known genera.
Alice J. Stelfox +6 more
doaj +1 more source
Uirusu, 2007 Our knowledge about envelope virus budding has been dramatically increased, since L-domain motifs were identified within their matrix and retroviral Gag proteins which drive virus budding. These viral proteins have been shown to interact with host cellular proteins involved in endocytosis and/or multi-vesicular body (MVB) sorting via their L-domains ...
IRIE, Takashi, SAKAGUCHI, Takemasa
openaire +3 more sources
Mechanisms of Oncolysis by Paramyxovirus Sendai [PDF]
Acta Naturae, 2015 Some viral strains of the Paramyxoviridae family may be used as anti-tumor agents. Oncolytic paramyxoviruses include attenuated strains of the measles virus, Newcastle disease virus, and Sendai virus. These viral strains, and the Sendai virus in particular, can preferentially induce the death of malignant, rather than normal, cells. The death of cancer
Matveeva, O. +4 more
openaire +3 more sources
A single amino acid substitution in the V protein of Nipah virus alters its ability to block interferon signalling in cells from different species [PDF]
, 2006 The V protein of the paramyxovirus Nipah virus (NiV) has been shown to antagonize the interferon (IFN) response in human cells via sequestration of STAT1 and STAT2.
Goodbourn, S +12 more
core +1 more source