Results 21 to 30 of about 15,173 (180)
Nipah Virus Efficiently Replicates in Human Smooth Muscle Cells without Cytopathic Effect
Cells, 2021 Nipah virus (NiV) is a highly pathogenic zoonotic virus with a broad species tropism, originating in pteropid bats. Human outbreaks of NiV disease occur almost annually, often with high case-fatality rates.
Blair L. DeBuysscher +5 more
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mBio, 2023 Increased viral surveillance has led to the isolation and identification of numerous uncharacterized paramyxoviruses, rapidly expanding our understanding of paramyxoviral diversity beyond the bounds of known genera.
Alice J. Stelfox +6 more
doaj +1 more source
Uirusu, 2007 Our knowledge about envelope virus budding has been dramatically increased, since L-domain motifs were identified within their matrix and retroviral Gag proteins which drive virus budding. These viral proteins have been shown to interact with host cellular proteins involved in endocytosis and/or multi-vesicular body (MVB) sorting via their L-domains ...
Takashi, Irie, Takemasa, Sakaguchi
openaire +3 more sources
Mechanisms of Oncolysis by Paramyxovirus Sendai [PDF]
Acta Naturae, 2015 Some viral strains of the Paramyxoviridae family may be used as anti-tumor agents. Oncolytic paramyxoviruses include attenuated strains of the measles virus, Newcastle disease virus, and Sendai virus. These viral strains, and the Sendai virus in particular, can preferentially induce the death of malignant, rather than normal, cells. The death of cancer
Matveeva, O. +4 more
openaire +3 more sources
mSphere, 2020 Between 2015 and 2017, routine molecular surveillance in the United States detected multiple mumps viruses (MuVs) with mutations in the small hydrophobic (SH) gene compared to a reference virus of the same genotype.
Rita Czakó Stinnett +7 more
doaj +1 more source
Structural and mechanistic studies of measles virus illuminate paramyxovirus entry.
PLoS Pathogens, 2011 Measles virus (MeV), a member of the paramyxovirus family of enveloped RNA viruses and one of the most infectious viral pathogens identified, accounts for major pediatric morbidity and mortality worldwide although coordinated efforts to achieve global ...
Richard K Plemper +2 more
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Sendai Virus-Vectored Vaccines That Express Envelope Glycoproteins of Respiratory Viruses
Viruses, 2021 Human respiratory syncytial virus (HRSV), human metapneumovirus (HMPV), and human parainfluenza viruses (HPIVs) are leading causes of respiratory disease in young children, the elderly, and individuals of all ages with immunosuppression.
Charles J. Russell, Julia L. Hurwitz
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The R2TP complex regulates paramyxovirus RNA synthesis.
PLoS Pathogens, 2019 The regulation of paramyxovirus RNA synthesis by host proteins is poorly understood. Here, we identified a novel regulation mechanism of paramyxovirus RNA synthesis by the Hsp90 co-chaperone R2TP complex.
Hiroshi Katoh +9 more
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Evidence that hPIV2 paramyxovirus antigenomes are edited during infection. [PDF]
mBioMononegavirus genomes contain cis-acting sequences that direct the formation of mRNA 5′ and 3′ ends during synthesis (gene start [GS] and gene end [GE]) but are silent during antigenome synthesis from the same genome template.
Ohta K +4 more
europepmc +2 more sources
Investigation of histopathological alteration of paramyxovirus-1 in naturally infected racing pigeons [PDF]
Iraqi Journal of Veterinary SciencesThe current study aimed to investigate the infection of racing pigeons with paramyxovirus-1(PMV-1) based on clinical signs of histological and histochemical changes, which increase the mortality rate in flocks called pigeons paramyxovirus.
Ayman A. Al-Alhially +2 more
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