Results 51 to 60 of about 28,213 (299)
Immune checkpoint inhibitors (ICI), i.e., anti-PD1/PDL1 and anti-CTLA-4, have reshaped the prognosis of many cancers. Increased use of ICI has led to the onset of new adverse events.
Morgan Zenatri +10 more
doaj +1 more source
Paraneoplastic antigens as biomarkers for early diagnosis of ovarian cancer
Paraneoplastic syndromes are a group of rare disorders that can be triggered by an abnormal immune response to proteins from tumors of the lung, ovary, lymphatics, or breast. Paraneoplastic clinical syndromes affect
Madhumita Chatterjee +2 more
doaj +1 more source
Spectrum of Neurologic Complications in Chronic Lymphocytic Leukemia [PDF]
Neurologic disease is believed to be an unusual complication during the course of chronic lymphocytic leukemia. Nevertheless, it has already been proven in autopsy series that the incidence of occult nervous system infiltration is much higher than was ...
Lopes Silva, R
core +1 more source
Paraneoplastic neurological syndromes
Summary Paraneoplastic neurological syndromes are immune-mediated erroneous attacks on the central or peripheral nervous systems, or both, directed originally against the tumour itself. They have been known for more than 40 years, but recently the discovery of new subgroups of paraneoplastic encephalitis syndromes with a remarkably good ...
F, Leypoldt, K-P, Wandinger
openaire +3 more sources
The Case of a 28‐Year‐Old Man With Gradually Progressive Proximal Leg Weakness
ABSTRACT This is a case of a 28‐year‐old man who presented with a 6‐month history of gradually progressive proximal leg weakness and pain that worsened on exercise and was relieved by rest. He had no symptoms in his upper limbs. Apart from intermittent mild ptosis and diplopia, he had no other cranial nerve symptoms.
Melody T. Asukile +3 more
wiley +1 more source
Longitudinally extensive transverse myelitis with AQP4 antibodies revealing ovarian teratoma. [PDF]
Paraneoplastic myelitis is a rare inflammatory disorder most frequently associated with solid tumors or lymphoproliferative disorders. Patients often harbor onconeuronal antibodies and their prognosis is usually poor.
Bataller, L. +9 more
core +1 more source
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye +11 more
wiley +1 more source
Paraneoplastic Leser-Trélat Syndrome: Clinical Manifestations, Diagnosis and Treatment
Examination of the skin is a widely available and simple method of examining the patient, which nevertheless allows you to diagnose systemic disorders and diseases in the human body at an early stage.
T. A. Gaydina +2 more
doaj +1 more source
Abstract Autoimmune encephalitis is a group of disorders characterized by symptoms of dysfunction of the limbic and extra‐limbic systems that occur in association with antibodies against intracellular antigens, synapses, or proteins located on the surface of nerve cells. Anti‐NMDA (N‐methyl‐D‐aspartate) receptor encephalitis was first described in 2007
Pham Ba Nha +6 more
wiley +1 more source
Summary: Background: Immune checkpoint inhibitor-related encephalitis (ICI-encephalitis) is not well characterised and diagnostic and prognostic biomarkers are lacking.
Antonio Farina +26 more
doaj +1 more source

