Results 71 to 80 of about 6,578 (194)
Alpha interferon restricts human T-lymphotropic virus type 1 and 2 De Novo infection through PKR activation [PDF]
International audienceType I interferon (IFN-I) inhibits the replication of different viruses. However, the effect of IFN-I on the human T-lymphotropic virus type 1 (HTLV-1) viral cycle is controversial.
Alais, Sandrine +7 more
core +4 more sources
A 62 year-old white female presented with a 10-year-history of slowly progressive spastic paraparesis, pain and dysesthesia in the lower limbs and sphincter disturbance.
Sônia Regina A. A. Pinheiro +5 more
doaj +1 more source
In order to evaluate the prevalence of HTLV-I infection and its association with tropical spastic paraparesis (TSP) in Bahia, a Northeastern State of Brazil, CSF and sera from TSP patients and CSF and/or sera from some selected groups of individuals were
O. A. Moreno-Carvalho +3 more
doaj +1 more source
Clinical phenotype and genetic associations in autosomal dominant familial Alzheimer's disease: a case series [PDF]
Background - The causes of phenotypic heterogeneity in familial Alzheimer’s disease with autosomal dominant inheritance are not well understood. We aimed to characterise clinical phenotypes and genetic associations with APP and PSEN1 mutations in ...
Adamson, G +15 more
core
Expression of alternatively spliced human T-cell leukemia virus type 1 mRNAs is influenced by mitosis and by a novel cis-acting regulatory sequence [PDF]
Human T-cell leukemia virus type 1 (HTLV-1) expression depends on the concerted action of Tax, which drives transcription of the viral genome, and Rex, which favors expression of incompletely spliced mRNAs and determines a 2-phase temporal pattern of ...
Bona, Marion K. +9 more
core +1 more source
Introduction: Human T cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) can impact the independence and motricity of patients.
Vera Lúcia Santos de Britto +2 more
doaj +1 more source
Quo vadis motor neuron disease? [PDF]
Motor neuron disease (MND), also known as amyotrophic lateral sclerosis, is a relentlessly progressive neurodegenerative condition that is invariably fatal, usually within 3 to 5 years of diagnosis. The aetio-pathogenesis of MND remains unresolved and no
Balendra, R, Patani, R
core +1 more source
“HTLV-I Infection” Twenty-Year Research in Neurology Department of Mashhad University of Medical Sciences [PDF]
Human T-cell lymphotropic virus (HTLV) types 1 and 2 belong to the Oncorna group of retroviridae, a large family of viruses, grouped initially by pathogenic features, but later revised on the basis of genome structure and nucleotide sequence.
Ali Shoeibi +4 more
doaj
HTLV-I associated myelopathy/tropical spastic paraparesis (TSP/HAM) have been increasingly described in practically all regions of Brazil. Five confirmed and documented cases of patients with TSP/HAM in Rio Grande do Sul are reported; in all of them ...
Márcio Menna-Barreto +3 more
doaj +1 more source
Human T-lymphotropic virus type 1 (HTLV-1) is the etiologic agent of both adult T-cell leukemia/lymphoma and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Satoshi Nozuma, Steven Jacobson
doaj +1 more source

