Results 1 to 10 of about 3,862 (200)

Partial Genome Characterization of Novel Parapoxvirus in Horse, Finland [PDF]

Emerging Infectious Diseases, 2023
We report a sequencing protocol and 121-kb poxvirus sequence from a clinical sample from a horse in Finland with dermatitis. Based on phylogenetic analyses, the virus is a novel parapoxvirus associated with a recent epidemic; previous data suggest ...
Jenni Virtanen, Maria Hautaniemi, Lara Dutra, Ilya Plyusnin, Katja Hautala, Teemu Smura, Olli Vapalahti, Tarja Sironen, Ravi Kant, Paula M. Kinnunen   +9 more
doaj   +4 more sources

A Comparison of Parapoxviruses in North American Pinnipeds [PDF]

Frontiers in Veterinary Science, 2021
Parapoxviruses cause nodular lesions on the skin and mucosal membranes of pinnipeds and infections by these viruses have been documented worldwide. Seal parapoxvirus is currently classified as a tentative species of the Parapoxvirus genus. Tissue or swab
Helena Costa, Helena Costa, Jörn Klein, Eva M. Breines, Hendrik H. Nollens, Keith Matassa, Mendy Garron, Padraig J. Duignan, Todd Schmitt, Tracey Goldstein, Morten Tryland   +10 more
doaj   +3 more sources

Orf Nodule with Erythema Multiforme during a Monkeypox Outbreak, France, 2022 [PDF]

Emerging Infectious Diseases, 2023
A 26-year-old patient in France who worked as a butcher sought care initially for erythema multiforme. Clinical examination revealed a nodule with a crusty center, which upon investigation appeared to be an orf nodule.
Charlotte Cavalieri, Anne-Sophie Dupond, Audrey Ferrier-Rembert, Olivier Ferraris, Timothée Klopfenstein, Souheil Zayet   +5 more
doaj   +2 more sources

Innate Immune Sensing of Parapoxvirus Orf Virus and Viral Immune Evasion [PDF]

Viruses
Orf virus (ORFV) is the type species of Parapoxvirus of the Poxviridae family that induces cutaneous pustular skin lesions in sheep and goats, and causes zoonotic infections in humans.
Basheer A. AlDaif, Stephen B. Fleming
doaj   +2 more sources

Orf mimicking a venous ulcer in the foot [PDF]

Journal of Global Infectious Diseases, 2023
Orf virus is a DNA virus belonging to the parapoxvirus family which is transmitted to humans by zoonotic routes through contact with infected animals. It is a worldwide spreading pathogen that can cause significant financial losses in animal production ...
Dua Cebeci, İlkay Can, Görgün Bayraktaroğlu   +2 more
doaj   +2 more sources

Erythema Multiforme post-Orf viral infection: a comprehensive review of the literature with a case report highlight [PDF]

Dermatology Reports
Orf, also known as ecthyma contagiosum, is a highly contagious zoonotic infection linked to direct contact with infected sheep, goats, or reindeer, posing a significant risk to farmers, veterinarians, shepherds, and butchers.
Mona Alkallabi, Khalid Nabil Nagshabandi, Shaden Alobaid , Reem Bin Idris, Amany Fathaddin   +4 more
doaj   +2 more sources

Immunomodulatory Strategies for Parapoxvirus: Current Status and Future Approaches for the Development of Vaccines against Orf Virus Infection

Vaccines, 2021
Orf virus (ORFV), the prototype species of the parapoxvirus genus, is the causative agent of contagious ecthyma, an extremely devastating skin disease of sheep, goats, and humans that causes enormous economic losses in livestock production. ORFV is known
Alhaji Modu Bukar, Faez Firdaus Abdullah Jesse, Che Azurahanim Che Abdullah, Mustapha M. Noordin, Zaharaddeen Lawan, Hassana Kyari Mangga, Krishnan Nair Balakrishnan, Mohd-Lila Mohd Azmi   +7 more
doaj   +1 more source

Parapoxvirus Interleukin-10 Homologues Vary in Their Receptor Binding, Anti-Inflammatory, and Stimulatory Activities

Pathogens, 2022
Homologues of interleukin (IL)-10, a pleiotropic immunomodulatory cytokine, have been identified in the Parapoxvirus genus. The first identified, Orf virus (ORFV) IL-10, greatly enhanced infection of its host, exhibiting immune modulatory effects ...
Amreen Naqash, Gabriella Stuart, Roslyn Kemp, Lyn Wise   +3 more
doaj   +1 more source

Pathogen surveillance in Southern Ocean pinnipeds

Polar Research, 2020
Knowledge of the health status and potential effect of disease outbreaks among Southern Ocean fauna may be decisive for its conservation. We assessed the exposure and infection of Antarctic fur seals (Arctocephalus gazella, AFS) and Southern elephant ...
Sandra Núñez-Egido, Andrew Lowther, Ingebjørg H. Nymo, Jörn Klein, Eva M. Breines, Morten Tryland   +5 more
doaj   +1 more source

Orf Virus-Based Vectors Preferentially Target Professional Antigen-Presenting Cells, Activate the STING Pathway and Induce Strong Antigen-Specific T Cell Responses

Frontiers in Immunology, 2022
BackgroundOrf virus (ORFV)-based vectors are attractive for vaccine development as they enable the induction of potent immune responses against specific transgenes. Nevertheless, the precise mechanisms of immune activation remain unknown.
Melanie Müller, Alena Reguzova, Markus W. Löffler, Markus W. Löffler, Markus W. Löffler, Markus W. Löffler, Ralf Amann   +6 more
doaj   +1 more source