Results 31 to 40 of about 690,789 (343)

The spectrum of clinical biomarkers in severe malaria and new avenues for exploration

open access: yesVirulence, 2022
Globally, malaria is a public health concern, with severe malaria (SM) contributing a major share of the disease burden in malaria endemic countries. In this context, identification and validation of SM biomarkers are essential in clinical practice. Some
Loick Pradel Kojom Foko   +6 more
doaj   +1 more source

A testis-expressing heme peroxidase HPX12 regulates male fertility in the mosquito Anopheles stephensi

open access: yesScientific Reports, 2022
In vertebrates dysregulation of the antioxidant defense system has a detrimental impact on male fertility and reproductive physiology. However, in insects, especially mosquitoes the importance of sperm quality has been poorly studied.
Seena Kumari   +10 more
doaj   +1 more source

Extensive Uncharted Biodiversity: The Parasite Dimension.

open access: yesIntegrative and Comparative Biology, 2018
Parasites are often hidden in their hosts and exhibit patchy spatial distributions. This makes them relatively difficult to detect and sample. Consequently we have poor knowledge of parasite diversities, distributions, and extinction.
B. Okamura, A. Hartigan, J. Naldoni
semanticscholar   +1 more source

CRISPR/Cas9 Genome Editing Reveals That the Intron Is Not Essential for var2csa Gene Activation or Silencing in Plasmodium falciparum

open access: yesmBio, 2017
Plasmodium falciparum relies on monoallelic expression of 1 of 60 var virulence genes for antigenic variation and host immune evasion. Each var gene contains a conserved intron which has been implicated in previous studies in both activation and ...
Jessica M. Bryant   +5 more
doaj   +1 more source

Transcriptional patterns of sexual dimorphism and in host developmental programs in the model parasitic nematode Heligmosomoides bakeri

open access: yesParasites & Vectors, 2023
Background Heligmosomoides bakeri (often mistaken for Heligmosomoides polygyrus) is a promising model for parasitic nematodes with the key advantage of being amenable to study and manipulation within a controlled laboratory environment.
Stephen M. J. Pollo   +5 more
doaj   +1 more source

Salivary glands harbor more diverse microbial communities than gut in Anopheles culicifacies

open access: yesParasites & Vectors, 2014
Background In recent years, it has been well documented that gut flora not only influence mosquito physiology, but also significantly alter vector competency.
Punita Sharma   +9 more
doaj   +1 more source

Comparison of the human-baited double net trap with the human landing catch for Aedes albopictus monitoring in Shanghai, China

open access: yesParasites & Vectors, 2018
Background Human landing catch (HLC) is the most efficient method for Aedes monitoring, but it is not ethical due to its high risk of human exposure to pathogens. We designed trials to assess the performance of an alternative human-baited double net trap
Qiang Gao   +7 more
doaj   +1 more source

AN ESTERASE-LIKE PROTEIN (ELP) CONFERRED MALATHION AND DELTAMETHRIN RESISTANCE IN THE INDIAN FIELD POPULATION OF ANOPHELES STEPHENSI

open access: yesInternational Journal of Infectious Diseases, 2023
Intro: Chemical insecticides in the form of IRS (Indoor Residual Sprays) and LLITNs (Long Lasting Insecticide Treated Nets) comprise current malaria vector control strategies.
J. Kumar   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Plasmodium falciparum Rosette Formation Assay

open access: yesBio-Protocol, 2013
Rosetting, i.e. the capacity of red blood cells (iRBCs) infected with mature parasite stages to bind two or more uninfected red blood cells (RBCs) is a virulence factor of Plasmodium falciparum.
Inès Vigan-Womas   +2 more
doaj   +1 more source

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