Results 41 to 50 of about 238,772 (243)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

HIF-1α hampers dendritic cell function and Th1 generation during chronic visceral leishmaniasis

Scientific Reports, 2018
Inflammation, although responsible for controlling infection, is often associated with the pathogenesis of chronic diseases. Leishmania donovani, the causative agent of visceral leishmaniasis, induces a strong inflammatory response that leads to ...
Akil Hammami, Belma Melda Abidin, Krista M. Heinonen, Simona Stäger   +3 more
doaj   +1 more source

Is Young's Modulus a Critical Coating Property Determining Fouling‐Release Performance of Marine Coatings?

Advanced Engineering Materials, EarlyView.
The release of foulers from protective marine coatings is determined by several interrelated material properties, including the strength of Young's modulus, the flexibility of chain segments, the surface free energy, and the magnitude of hydrodynamic stress.
Johann C. Schaal, Andreas Brinkmann, Andreas Hartwig   +2 more
wiley   +1 more source

A Synergistic Transcriptional Regulation of Olfactory Genes Drives Blood-Feeding Associated Complex Behavioral Responses in the Mosquito Anopheles culicifacies

Frontiers in Physiology, 2018
Decoding the molecular basis of host seeking and blood feeding behavioral evolution/adaptation in the adult female mosquitoes may provide an opportunity to design new molecular strategy to disrupt human-mosquito interactions.
Tanwee Das De, Tanwee Das De, Tina Thomas, Sonia Verma, Deepak Singla, Charu Chauhan, Vartika Srivastava, Punita Sharma, Seena Kumari, Sanjay Tevatiya, Jyoti Rani, Yasha Hasija, Kailash C. Pandey, Kailash C. Pandey, Rajnikant Dixit   +14 more
doaj   +1 more source

Genetic polymorphism of circumsporozoite protein of Plasmodium falciparum among Chinese migrant workers returning from Africa to Henan Province

Malaria Journal, 2022
Background Plasmodium falciparum malaria is recognized as a major global public health problem. The malaria vaccine was important because the case fatality rate of falciparum malaria was high. Plasmodium falciparum circumsporozoite protein (PfCSP) is one
Zhi-quan He, Qun-qun Zhang, Dan Wang, Ya-bo Hu, Rui-min Zhou, Dan Qian, Cheng-yun Yang, De-ling Lu, Su-hua Li, Ying Liu, Hong-wei Zhang   +10 more
doaj   +1 more source

Advancing Research on Biomaterials and Biological Materials with Scanning Electron Microscopy under Environmental and Low Vacuum Conditions

Advanced Engineering Materials, EarlyView.
Herein, environmental scanning electron microscopy (ESEM) is discussed as a powerful extension of conventional SEM for life sciences. By combining high‐resolution imaging with variable pressure and humidity, ESEM allows the analysis of untreated biological materials, supports in situ monitoring of hydration‐driven changes, and advances the functional ...
Jendrian Riedel, Lea Dierker, Antoine Eyram Kwame, Kim Nora Wagner, Jonas J. Unterholzner, Jan‐Henning Dirks, Dorothea Brüggemann   +6 more
wiley   +1 more source

Impact of Titanium Mining and Other Anthropogenic Activities on Malaria Positivity Rates and Parasitemia in Five Selected Study Sites in Msambweni Subcounty, Kwale County, Kenya

Journal of Parasitology Research
Africa was home to 95% of malaria cases and deaths in 2021. The negative impacts of malaria can be aggravated by social–economic–environmental factors, more so agroeconomic practices such as irrigation, mining, and dam construction. The aim of this study
Edward Githinji, Collins Okoyo, Cassian Mwatele, Juma Mwatasa, Benard Chieng, Sylvie Araka, Henry Kanyi, Sammy Njenga, Judy Mwai   +8 more
doaj   +1 more source

Laser Metal Powder Deposition of Titanium Microalloyed HSLA Steel FeC0.12Si0.25Mn1.3

Advanced Engineering Materials, EarlyView.
This study investigates the additive manufacturing of titanium‐doped high‐strength low‐alloy (HSLA) steel via laser metal deposition. It reveals distinct process‐structure relationships for elemental powder blends compared to prealloyed feedstocks.
Olaf Stelling, Matthias Steinbacher, Nils Ellendt   +2 more
wiley   +1 more source

Molecular and Functional Characterization of Trehalase in the Mosquito Anopheles stephensi

Frontiers in Physiology, 2020
Like other insects, in blood-feeding mosquitoes, trehalase (TRE; EC 3.2.1.28), an enzyme that metabolizes trehalose, may influence a wide array of functions including flight, survival, reproduction, and vectorial capacity, but its role has not been ...
Sanjay Tevatiya, Seena Kumari, Punita Sharma, Jyoti Rani, Charu Chauhan, Tanwee Das De, Kailash C. Pandey, Veena Pande, Rajnikant Dixit   +8 more
doaj   +1 more source