Results 71 to 80 of about 52,532 (272)

Parasite Burden of Trypanosoma cruzi in Whole Blood and Buffy Coat Determined by Real-Time PCR in Individuals with Chronic Chagas Disease

Microorganisms
The objective of this study was to compare, by qPCR, the circulating blood parasite load of Trypanosoma cruzi in the buffy coat, and in whole blood mixed with boiled and unboiled guanidine hydrochloride-EDTA buffer, of individuals with chronic ChD.
Daniela Liempi, Inés Zulantay, Nelson M. Varela, Mauricio Canals, Andrés Guevara, Nicolás Poulsen, Werner Apt   +6 more
doaj   +1 more source

In vivo assessment of drug efficacy against Plasmodium falciparum malaria: duration of follow-up. [PDF]

, 2004
To determine the optimum duration of follow-up for the assessment of drug efficacy against Plasmodium falciparum malaria, 96 trial arms from randomized controlled trials (RCTs) with follow-up of 28 days or longer that were conducted between 1990 and 2003
Adjuik, M, Barnes, K, Day, N P J, Farrar, J, Guthmann, J P, Hien, T T, Looareesuwan, S, Mayxay, M, Myint, H Y, Nosten, F, Olliaro, P, Price, R, Pukrittayakamee, S, Smithuis, F, Stepniewska, K, Taylor, W R J, White, N J   +16 more
core   +3 more sources

Oral melatonin improves the detection of parasitemia in malaria

The Journal of Infection in Developing Countries, 2020
Introduction: Malaria is a growing global threat and a major cause of mortality in the tropics. The gold standard diagnosis is peripheral blood smear examination. It has been demonstrated that melatonin acts as messenger molecule in malaria pathophysiology.
Chandan Kumar Kedarisetty, B Laksminarayana Samaga, Sudha Vidyasagar, Jayanthi Venkataraman   +3 more
openaire   +4 more sources

Imaging malaria parasites across scales and time

Journal of Microscopy, EarlyView.
Abstract The idea that disease is caused at the cellular level is so fundamental to us that we might forget the critical role microscopy played in generating and developing this insight. Visually identifying diseased or infected cells lays the foundation for any effort to curb human pathology.
Julien Guizetti
wiley   +1 more source

Trypanosoma evansi as a Major Cause of Animal Trypanosomiasis: A Comprehensive Review

Jurnal Medik Veteriner
Trypanosomiasis caused by Trypanosoma evansi is a major protozoan illness that affects animals worldwide. It is also referred to as “surra” and affects a variety if wild and domestic animals such as sheep, cattle, goats, dogs, buffaloes, pigs, elephants,
Sunaryo Hadi Warsito, Aswin Rafif Khairullah, Mirni Lamid, Mohammad Anam Al-Arif, Herry Agoes Hermadi, Widya Paramita Lokapirnasari, Muhammad Khaliim Jati Kusala, Syahputra Wibowo, Siti Rani Ayuti, Bantari Wisynu Kusuma Wardhani, Ima Fauziah, Sheila Marty Yanestria, Ikechukwu Benjamin Moses, Agung Prasetyo, Suhita Aryaloka, Kartika Afrida Fauzia, Riza Zainuddin Ahmad, Dea Anita Ariani Kurniasih   +17 more
doaj   +1 more source

TcI isolates of Trypanosoma cruzi exploit the antioxidant network for enhanced intracellular survival in macrophages and virulence in mice [PDF]

, 2016
Trypanosoma cruzi species is categorized into six discrete typing units (TcI to TcVI) of which TcI is most abundantly noted in the sylvatic transmission cycle and considered the major cause of human disease. In our study, the TcI strains Colombiana (COL),
Basombrío, Miguel Ángel Manuel, Dhiman, Monisha, Garg, Nisha J., Hosakote, Yashoda M., Koo, Sue Jie, Parodi­ Talice, Adriana, Piñeyro, María Dolores, Robello, Carlos, Zago, María Paola   +8 more
core   +2 more sources

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, EarlyView.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

Optimisation of freeze substitution protocols for the examination of malaria parasite structure by volumetric electron microscopy

Journal of Microscopy, EarlyView.
Abstract Malaria is one of the deadliest infectious diseases in the world, annually responsible for over 400,000 deaths. It is caused by parasites of the genus Plasmodium, which undergo remarkable structural changes during their development within different cells across various hosts.
Rachel Rachid, Camila Wendt, Wanderley de Souza, Kildare Miranda   +3 more
wiley   +1 more source

An Automated Microscopic Malaria Parasite Detection System Using Digital Image Analysis

Diagnostics, 2021
Rapid diagnosis and parasitemia measurement is crucial for management of malaria. Microscopic examination of peripheral blood (PB) smears is the gold standard for malaria detection. However, this method is labor-intensive.
Jung Yoon, Woong Sik Jang, Jeonghun Nam, Do-CiC Mihn, Chae Seung Lim   +4 more
doaj   +1 more source

Evolution of malaria virulence in cross-generation transmission through selective immune pressure [PDF]

, 2007
Theoretical arguments and some mathematical models of host-parasite coevolution (e.g. [1- 6]) suggest host immunity as the driving source for the evolution of parasite virulence.
David E. Gurarie
core   +2 more sources