Results 21 to 30 of about 1,133 (164)

Prevalence and Duration of Potential Drug–Drug Interactions Among US Nursing Home Residents, 2018–2020

open access: yesJournal of the American Geriatrics Society, Volume 73, Issue 12, Page 3766-3777, December 2025.
ABSTRACT Background Nursing home (NH) residents are at increased risk of drug–drug interactions (DDIs) due to multimorbidity and polypharmacy. While prior research suggests that many DDIs lead to adverse drug events in older adults, the extent of exposure to potentially clinically relevant DDIs among United States (US) NH residents is largely unknown ...
Laura A. Reich   +9 more
wiley   +1 more source

Effect of N‐Butylscopolammonium Bromide and Metamizol Sodium on Heart Rate, Blood Pressure, and Echocardiographic Measurements in Warmblood Horses With Aortic and Mitral Valve Regurgitation

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 6, November/December 2025.
ABSTRACT Background Administration of N‐butylscopolammonium bromide (NBB) with metamizol sodium (NBBM) causes tachycardia and hypertension, and has been associated with accentuated cardiac murmurs. Objectives To evaluate the effect of a pharmacological challenge using NBBM on valvular regurgitation and cardiac murmurs in horses with aortic (AR) and ...
Alexander Dufourni   +6 more
wiley   +1 more source

Autonomic effects of electroacupuncture in opioid‐induced constipation in male rats

open access: yesPhysiological Reports, Volume 13, Issue 19, October 2025.
Abstract The efficacy of electroacupuncture (EA) for opioid‐induced constipation (OIC) has been reported; however, the mechanism has not been sufficiently studied, and the details have not been clarified. The aims of this study were to demonstrate the delay in rat colonic transit (CT) caused by loperamide, a peripheral μ‐opioid receptor agonist, and to
Misaki Okada   +3 more
wiley   +1 more source

Around the EQUATOR With Clin‐STAR: Systematic Reviews of Intervention Effectiveness; Challenges and Opportunities

open access: yesJournal of the American Geriatrics Society, Volume 73, Issue 8, Page 2356-2365, August 2025.
ABSTRACT Systematic reviews offer clarity about the effectiveness of interventions based on the best available evidence. The Preferred Reporting Items for Systematic reviews and Meta‐Analyses (PRISMA) 2020 statement updated previous guidance to ensure transparency in the reporting of systematic reviews of intervention effectiveness. To adhere to the 27
Thomas F. Crocker   +2 more
wiley   +1 more source

RECOVER Guidelines: Newborn Resuscitation in Dogs and Cats. Evidence and Knowledge Gap Analysis With Treatment Recommendations

open access: yesJournal of Veterinary Emergency and Critical Care, Volume 35, Issue S1, Page 3-59, August 2025.
ABSTRACT Objective To systematically review the evidence on, to devise clinical recommendations for, and to identify critical knowledge gaps in resuscitation of newborn puppies and kittens. Design Standardized, systematic evaluation of literature pertinent to newborn resuscitation following Grading of Recommendations, Assessment, Development, and ...
Manuel Boller   +63 more
wiley   +1 more source

The anticholinergic burden in patients with chronic kidney disease: Patterns, risk factors, and the link with cognitive impairment

open access: yesJournal of the American Geriatrics Society, Volume 73, Issue 2, Page 533-544, February 2025.
Abstract Background People with chronic kidney disease (CKD) have an elevated risk of cognitive impairment (CI). Medications with anticholinergic activity are recognized for their adverse reactions on central nervous system. The putative association between the anticholinergic burden and CI has not previously been evaluated in patients with CKD.
Agathe Mouheb   +73 more
wiley   +1 more source

2024 RECOVER Guidelines: Advanced Life Support. Evidence and knowledge gap analysis with treatment recommendations for small animal CPR

open access: yesJournal of Veterinary Emergency and Critical Care, Volume 34, Issue S1, Page 44-75, July/August 2024.
Abstract Objective To systematically review the evidence and devise clinical recommendations on advanced life support (ALS) in dogs and cats and to identify critical knowledge gaps. Design Standardized, systematic evaluation of literature pertinent to ALS following Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology.
Jacob Wolf   +46 more
wiley   +1 more source

Twenty‐four hour continuous transvenous temporary right ventricular pacing in healthy horses

open access: yesJournal of Veterinary Internal Medicine, Volume 38, Issue 3, Page 1751-1764, May/June 2024.
Abstract Background The ability to perform transvenous temporary cardiac pacing (TV‐TP) is critical to stabilize horses with symptomatic bradyarrhythmias. Reports of successful TV‐TP in horses are limited, and only briefly describe short‐term pacing.
Amanda Avison   +9 more
wiley   +1 more source

Effect of physiological and pharmacological stress on heart rate, blood pressure, and echocardiographic measurements in healthy Warmblood horses

open access: yesJournal of Veterinary Internal Medicine, Volume 38, Issue 1, Page 398-410, January/February 2024.
Abstract Background Echocardiographic measurements are important prognostic indicators but might be influenced by heart rate and blood pressure. This is particularly important when comparing repeated examinations. Hypothesis To determine the effect of physiological stress at mildly increased heart rates and pharmacological challenge using IV ...
Alexander Dufourni   +5 more
wiley   +1 more source

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