Combined Effects of Romosozumab and Zoledronate on the Development of Osteonecrosis of the Jaw
ABSTRACT Objective This study aimed to assess the occurrence of medication‐related osteonecrosis of the jaw (MRONJ) in mice following the sequential administration of romosozumab and zoledronate and to confirm their inhibitory effects on osteoclast differentiation in vitro.
Hae‐Seo Park +5 more
wiley +1 more source
ABSTRACT Objective Head and neck cancer radiotherapy can lead to jaw osteoradionecrosis (ORN). There is currently no definitive treatment for ORN. The efficacy of a novel orally delivered aglycosylated IGF‐1 with an E‐peptide (CTB‐Pro‐IGF‐1), bioencapsulated in plant cells, was evaluated as therapy for jaw ORN in rats. Materials and Methods Rat jaw ORN
Sunday O. Akintoye +5 more
wiley +1 more source
Surgical Treatment of Tumor‐Induced Osteomalacia With Causative Tumors Affecting the Long Bones
Tumor‐induced osteomalacia (TIO) is an extremely rare paraneoplastic syndrome with an insidious onset. Consequently, the orthopedic surgical strategies for TIO urgently require refinement, and an international consensus must be established. The causative tumors of TIO located in the long bones are occult and exhibit diverse anatomical distributions ...
Shuzhong Liu +7 more
wiley +1 more source
Parathyroid hormone-related protein-mediated hypercalcemia of malignancy: insights from a multicenter clinical data warehouse. [PDF]
Kim J +12 more
europepmc +1 more source
Plasma thyrocalcitonin and parathyroid hormone concentrations in early neonatal hypocalcaemia
During the first week of life serum calcium, phosphorus, magnesium, immunoreactive thyrocalcitonin hormone, and parathyroid hormone concentrations were determined daily in 36 preterm and 29 small for gestational age, full term, healthy infants.
Romagnoli, Costantino +2 more
core
Relationship between vitamin D deficiency and early implant failure and osseointegration
Abstract Background This systematic review investigated the relationship between pre‐operative vitamin D levels and implant osseointegration and implant‐related outcomes. It also assessed studies involving vitamin D supplementation before implant placement.
Richard J. Miron +8 more
wiley +1 more source
Efficacy and safety of parathyroid hormone analogs therapy on hypoparathyroidism: a meta-analysis. [PDF]
Li S, Zhang Y, Zhao L, Ma C.
europepmc +1 more source
Bone biology in aging periodontal and peri‐implant tissues
Abstract Background Periodontal disease is an age‐related chronic inflammatory condition leading to tooth loss. Dental implants are an option for replacement of lost teeth in older adults. However, age‐related changes to alveolar bone may have pathological implications for its role in supporting the dentition and dental implants.
Dalia Rasheed Issa +2 more
wiley +1 more source
Parathyroid hormone levels and sarcopenia in dialysis patients: absence of association or methodological limitations? [PDF]
Morais ACC, Santos CGDS, Barreto FC.
europepmc +1 more source
Understanding exosomes in diabetic wound healing
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad +4 more
wiley +1 more source

