Results 171 to 180 of about 510,425 (296)

Associations of parathyroid hormone and atrial fibrillation: epidemiological insights from the LURIC study. [PDF]

open access: yesFront Cardiovasc Med
König L   +9 more
europepmc   +1 more source

Musculoskeletal decay and bone–muscle crosstalk during physical disuse: Mechanisms and integrated countermeasures

open access: yesExperimental Physiology, EarlyView.
Abstract Older adults experience a markedly increased risk of falls and fractures following hospital discharge, largely due to the rapid musculoskeletal deterioration associated with bed rest. Although age‐related muscle and bone loss typically develops gradually, acute physical inactivity accelerates key biological processes underlying sarcopenia and ...
Julia Margarita Reyes   +5 more
wiley   +1 more source

Giant Parathyroid Adenoma Masked by Severe Vitamin D Deficiency with Hypocalcemic Presentation: A Case Report

open access: yesInternational Medical Case Reports Journal
Bana Khalil,1,* Ali Chiha,2,* Alyamama Kousa,3 Anass Alrez,4 Aya Alayyoubi,5 Ahmad Abdul Hakim Alhamid,6 Areen Glore7 1Faculty of Medicine, Tishreen University, Latakia, Syria; 2School of Medicine, St. George’s University, St.
Khalil B   +6 more
doaj  

Spatial control of parathyroid hormone receptor-1 signaling dictates ligand-specific biological outcomes. [PDF]

open access: yesSignal Transduct Target Ther
Höppner J   +11 more
europepmc   +1 more source

Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang   +16 more
wiley   +1 more source

Self‐Assembly of Therapeutic Peptides for Enhanced Cancer Therapy: Strategies, Therapeutic Performance, and Future Perspectives

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Therapeutic peptide self‐assembly is governed by multiple non‐covalent interactions, enabling the construction of diverse supramolecular structures. These self‐assembled systems can be engineered through spontaneous self‐assembly of monomers, co‐assembly, or stimulus‐responsive strategies to improve tumor delivery efficiency.
Yuelin Fang   +6 more
wiley   +1 more source

Peptide‐Linked Bivalent Nanobody Constructs as Positive Allosteric Modulators of the Calcium‐Sensing Receptor

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 6, December 2026.
ABSTRACT We previously developed nanobodies acting as positive allosteric modulators (PAMs) of the calcium‐sensing receptor (CaSR). Here, we sought to develop more potent CaSR modulators by creating bivalent nanobody constructs using ‘tail‐to‐head’ peptide‐linker conjugation.
Mahdis Nabipour   +5 more
wiley   +1 more source

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