Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency
ABSTRACT Primary pyruvate dehydrogenase complex deficiency (PDCD) comprises a group of monogenic disorders caused by pathogenic variants in genes encoding subunits of, or regulatory components affecting, the pyruvate dehydrogenase complex. The clinical phenotype spans a broad continuum, ranging from early onset congenital lactic acidosis to infantile ...
Nandaki Keshavan +23 more
wiley +1 more source
Postoperative Hypocalcemia Following Total Thyroidectomy Versus Completion Thyroidectomy
Completion thyroidectomy performed with at least a three‐month interval demonstrates superior parathyroid preservation compared to primary total thyroidectomy, as evidenced by significantly higher postoperative parathyroid hormone levels (51.90 ± 30.26 pg/mL vs. 30.90 ± 17.10 pg/mL, p = 0.006).
Mehmet Turan Cicek +3 more
wiley +1 more source
An Unusual Etiology of Recurrent Parathyroid Hormone-Independent Hypercalcemia. [PDF]
Thakkar S +5 more
europepmc +1 more source
Exosomes in Cancer: The Biology, Function, Diagnosis, and Therapy
Tumor‐derived exosomes and nonmembranous extracellular nanoparticles (exomeres/supermeres) constitute a heterogeneous communication network that drives cancer progression. By shuttling functional biomolecules across tissue‐specific barriers, these nanoparticles orchestrate local microenvironmental remodeling, immune suppression, premetastatic niche ...
Jun Wu +8 more
wiley +1 more source
Predicting permanent hypoparathyroidism after thyroidectomy: role of early postoperative parathyroid hormone levels and surgical factors. [PDF]
Akmercan A +5 more
europepmc +1 more source
Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang +4 more
wiley +1 more source
Kidney Transplant Complicated by Severe Parathyroid Hormone-Independent Hypercalcemia From Tumoral Calcinosis. [PDF]
Volety A +5 more
europepmc +1 more source
In a dog with thyroid carcinoma and equivocal preoperative imaging findings, intraoperative assessment of venous involvement was aided by indocyanine green fluorescence imaging during thyroidectomy. Segmental intraluminal fluorescence within the dilated thyroid vein informed extension of the resection margin, allowing en bloc removal of the tumour and ...
Mingyeong Kim, Yujin Kim, Sungin Lee
wiley +1 more source
Parathyroid Hormone Related Peptide (PTHrP) Revisited: A Comparison of Levels in Malignant and Non-malignant Conditions. [PDF]
Ling G, Akande R, Albert SG.
europepmc +1 more source

