Results 201 to 210 of about 73,750 (259)

Parathyroid hormone

2021
Parathyroid hormone is an essential regulator of extracellular calcium and phosphate. PTH enhances calcium reabsorption while inhibiting phosphate reabsorption in the kidneys, increases the synthesis of 1,25-dihydroxyvitamin D, which then increases gastrointestinal absorption of calcium, and increases bone resorption to increase calcium and phosphate ...
openaire   +2 more sources

Parathyroid Hormone and Phosphaturia

Calcified Tissue Research, 1975
In 1911, Greenwald reported that urinary phosphate was significantly decreased in parathyroidectomized dogs (3). He was the first to suggest a link between the observed drop in phosphate excretion and the removal of the parathyroid glands. Sixty-four years later, the mechanism by which parathyroid hormone (PTH) enhances phosphaturia is still largely ...
T, Uchikawa, A B, Borle, R J, Midgett
openaire   +2 more sources

BIOSYNTHESIS OF PARATHYROID HORMONE

Annals of the New York Academy of Sciences, 1977
Figure 11 summarizes our present concepts of the biosynthetic sequence for parathyroid hormone, deduced largely from observations in vitro. Many aspects of the presumed process whereby preproparathyroid hormone is converted via proparathyroid hormone to the hormone remain unclarified and require much further study, as is true for many other prehormones.
J T, Potts, H M, Kronenberg, J F, Habener, A, Rich   +3 more
openaire   +3 more sources

Parathyroid hormone and parathyroid hormone-related peptide, and their receptors

Biochemical and Biophysical Research Communications, 2005
Parathyroid hormone (PTH) has a central role in the regulation of serum calcium and phosphate, while parathyroid hormone-related peptide (PTHrP) has important developmental roles. Both peptides signal through the same receptor, the PTH/PTHrP receptor (a class B G-protein-coupled receptor).
Robert C, Gensure, Thomas J, Gardella, Harald, Jüppner   +2 more
openaire   +2 more sources

Parathyroid Hormone and Parathyroid hormone-Related Protein

The Biomedical & Life Sciences Collection, 2001
Publisher Summary This chapter focuses on current understanding of the physiology and mechanism of action of these polypeptides. Parathyroid hormone (PTH) and PTH-related protein (PTHrP) are major factors that regulate skeletal physiology and mineral homeostasis.
openaire   +1 more source

Parathyroid Hormone Radioimmunoassay

Annals of Internal Medicine, 1979
Excerpt The study by Raisz and colleagues reported in this issue (1), although based on a small number of samples, illustrates both the assets and limitations of commercially available radioimmunoa...
J F, Habener, G V, Segre
openaire   +2 more sources

Oxidation of parathyroid hormone

Clinica Chimica Acta, 2020
Parathyroid hormone (PTH) is the key hormone regulating calcium homeostasis and, as such, is an important diagnostic and prognostic marker. Although the measurement of PTH has greatly improved over the past few decades, oxidation status thereof is unaccounted for in currently used assays. PTH can be oxidized on methionine residues located at amino acid
Stan R. Ursem, Marc G. Vervloet, Renate T. de Jongh, Annemieke C. Heijboer   +3 more
openaire   +2 more sources

Pro-Parathyroid Hormone

Annals of Internal Medicine, 1972
Excerpt To the editor: We read with great interest the editorial by Drs. Gordan and Roof, "Humors from Tumors": "Diagnostic Potential of Peptides" (1).
J F, Habener, B, Kemper
openaire   +2 more sources

The Parathyroid Hormone Assay

Endocrine Practice, 2011
To review the history and application of laboratory assays for the measurement of parathyroid hormone.Perinent literature documenting the development of the parathyroid hormone assay was reviewed.Following its introduction in 1963, the parathyroid hormone assay has evolved into a highly sensitive and specific test.
Steven E, Rodgers, John I, Lew
openaire   +2 more sources