Results 21 to 30 of about 103,853 (302)

Discontinuing Long‐Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?

Clinical Pharmacology &Therapeutics, EarlyView.
Discontinuation of denosumab (Dmab) may be necessary due to adverse events or an unfavorable long‐term risk–benefit profile. However, accumulating evidence demonstrates pronounced rebound phenomena after withdrawal, most notably a marked increase in multiple vertebral fractures, and, in some reports, elevated mortality.
Ko‐Hsiu Lu, Renn‐Chia Lin, Ing‐Lin Chang, Shau‐Huai Fu, Meng‐Ying Tsai, Shun‐Fa Yang   +5 more
wiley   +1 more source

Biosynthesis of Proparathyroid Hormone and Parathyroid Hormone by Human Parathyroid Glands [PDF]

Journal of Clinical Investigation, 1973
Human parathyroid glands obtained at autopsy were incubated with [(3)H]leucine and [(3)H]lysine. After incubation, nonradioactive parathyroid tissue of either human or bovine origin was added. Radioactive parathyroid hormone and proparathyroid hormone were isolated from the gland and medium by organic solvent and salt fractionation, trichloroacetic ...
L L, Chu, R R, MacGregor, P I, Liu, J W, Hamilton, D V, Cohn   +4 more
openaire   +2 more sources

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Impaired Insulin sensitivity and Insulin secretion in Haemodialysis patients with and without Secondary Hyperparathyroidism [PDF]

, 2004
The aim of our study was to investigate insulin sensitivity and beta cell function in hemodialysis (HD) patients without diabetes. We hypothesized that parathyroid gland function was a determinant of insulin sensitivity and/or beta cell function.
Pljesa, Steva, Komadina, Ljiljana, Milic, Natasa, Rasic-Milutinovic, Zorica, Gluvic, Zoran M., Perunicic-Pekovic, Gordana   +5 more
core  

Cardiovascular actions of parathyroid hormone and parathyroid hormone-related peptide [PDF]

Cardiovascular Research, 1998
Cardiovascular cells (cardiomyocytes and smooth muscle cells) are target cells for parathyroid hormone (PTH) and the structurally related peptide parathyroid hormone-related peptide (PTH-rP). PTH activates protein kinase C (PKC) of cardiomyocytes via a PKC activating domain previously identified on chondrocytes.
K D, Schlüter, H M, Piper
openaire   +2 more sources

Women with epilepsy: Evidence‐based counseling across the lifespan

Epilepsia, EarlyView.
Abstract Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex‐specific aspects of epilepsy has increased, important gaps remain in their integration into routine care.
Barbara Tettenborn, Georgia Ramantani, Dominique Flügel, Verena Gaus, Susanne Schubert‐Bast, Elisabeth Sellitto, Jennifer Bausch, Bettina Schmitz   +7 more
wiley   +1 more source

A Case of Mediastinal Parathyroid Adenoma

, 2015
Parathyroid adenomas are the most important cause of primary hyperparathyroidism. The diagnosis of primary hyperparathyroidism is established based on the combination of elevated serum calcium and parathyroid hormone levels.
Erkan Akar
core   +1 more source

Cancer Risk in Marfan Syndrome: A Swedish Population‐Based Cohort Study

International Journal of Cancer, EarlyView.
The cancer risk in Marfan syndrome, an autosomal dominant connective tissue disorder, largely remains to be explored. In this population‐based matched cohort study of 1544 Swedish patients, the overall cancer risk in adults with Marfan syndrome showed no significant increase, except for the risk of endocrine tumours with a nearly threefold increase ...
Ida Nordgren, Anna Skarin Nordenvall, Alexandra Wachtmeister, Fulya Taylan, Yunxia Lu, Christina Norrby, Anna Lindstrand, Giedre Grigelioniene, Giorgio Tettamanti   +8 more
wiley   +1 more source

Parathyroid Hormone Dysfunction

, 2015
Phosphorus-calcium homeostasis is regulated by parathyroid hormone(PTH). A primary (parathyroid gland adenoma or hyperplasia) or secondary (chronic renal failure or vitamin D deficiency) excess of this hormone or a PTH defect (hypoparathyroidism) has ...
Rosa M. Sánchez, Ana María Wägner, Wägner, Anna Maria Claudia, Sánchez, Rosa M.   +3 more
core   +1 more source

Placental transfer of parathyroid hormone [PDF]

, 1986
Balabanova et al, Placental transfer of parathyroid hormone ...
Ulrich Vetter, Thomas Lang, Gerhard Gaedicke, Ivo Henrichs, Alfred S. Wolf, J. Perinat Med, Teller, Walter M., Walter M. Teller, Svetla Balabanova, Gaedicke, Gerhard, Vetter, Ulrich, Wolf, Alfred S., Henrichs, Ivo, Janos Homoki, Homoki, Janos, Lang, Thomas, Balabanova, Svetla   +16 more
core   +1 more source