Results 41 to 50 of about 510,425 (296)

Laboratory and instrumental criteria for assessing the persistence of primary hyperparathyroidism within the first day after surgery. Retrospective assessment of risk

Mìžnarodnij Endokrinologìčnij Žurnal, 2019
Background. The variability of laboratory results leads to an in­depth study of the past medical history and clinical picture, as well as diagnostic procedures to detect parathyroid glands with altered functional activity. The purpose of the study was to
P.O. Lishchynski, V.O. Palamarchuk, O.P. Nechay, M.A. Urina, O.A. Tovkay, V.V. Kutz   +5 more
doaj   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

The Diagnostic Accuracy of High Resolution Ultrasound Imaging for Detection of Secondary Hyperparathyroidism in Patients with Chronic Renal Failure [PDF]

Acta Medica Iranica, 2011
Ultrasound is one of the preferred modalities for evaluation of the parathyroid glands. This study was undertaken to determine the accuracy of high resolution ultrasound for secondary hyperparathyroidism in patients with chronic renal failure. From March
Hassan Anari, Bahman Bashardoust, Masoud Pourissa, Soheila Refahi   +3 more
doaj   +1 more source

Sustainable Hydrogel‐Forming Microneedle‐Reservoir Patches for Transdermal Delivery of Hydrophilic Macromolecules: Biopolymers, Green Manufacturing and Translation

Advanced Science, EarlyView.
Hydrogel‐forming microneedle (HFMN)‐reservoir patches provide a modular route for controlled transdermal delivery of hydrophilic biomacromolecules. The platform integrates skin‐barrier penetration, sustainable biopolymers, scalable green manufacturing, hydration‐driven transport, model‐cargo validation, and translational quality requirements.
Siddharth Mohanty, Mehmet Onur Aydogdu, Sijia Kang, Xinbo Li, Mohan Edirisinghe   +4 more
wiley   +1 more source

Refractory hypercalcemia caused by parathyroid-hormone-related peptide secretion from a metastatic pancreatic neuroendocrine tumor: a case report

Journal of Medical Case Reports
Background The parathyroid-hormone-related peptide has been shown in earlier studies to be secreted by pancreatic neuroendocrine tumors, although its secretion by gastroenteropancreatic neuroendocrine tumors is very rare.
Motti Haimi, Ji Wei Yang, Richard Kremer
doaj   +1 more source

A case of extrapulmonary tuberculosis in a patient with end-stage renal disease with elevated parathyroid hormone–related protein

SAGE Open Medical Case Reports, 2020
The diagnosis of extrapulmonary tuberculosis in patients with end-stage renal disease can be challenging as the signs and symptoms are often non-specific.
Shreya Podder, Katarina Fleckenstein, Zehra Gaudiano   +2 more
doaj   +1 more source

Diagnostic approach to hypercalcemia: relevance of parathyroid hormone and parathyroid hormone-related protein measurements

, 2001
Background: Parathyroid hormone (PTH) and parathyroid hormone-related protein (PTH-rP) are two potent hypercalcemic hormones that act on the same targets.
Jaeger, P, Kurt Lippuner, Casez, J -P., Quan-Vinh Nguyen, Jean-Paul Casez, Nguyen, Q -V., Philippe Jaeger, Rahel Pfammatter, Lippuner, K, Pfammatter, R   +9 more
core   +1 more source

Fuyuan Huoxue Decoction Promotes Lumbar Interbody Fusion in Rats: Role of Macrophage‐Driven Inflammation and the TLR9/NF‐κB Pathway

Advanced Science, EarlyView.
Fuyuan Huoxue decoction improves lumbar interbody fusion in rats while reducing inflammatory macrophage activity and supporting bone‐forming stem cells. Experiments implicate extracellular DNA and TLR9/NF‐κB signaling in early responses. These findings point to coordinated control of inflammation and osteogenesis as a potential route to stronger spinal
Hongwei Gao, Han Wu, Shaorong Li, Weijian Wang, Yijian Guo, Shuai Cheng, Jiayi Sun, Jilong An, Wei Zhang   +8 more
wiley   +1 more source

Sarcopenia and Sarcopenic Obesity in Postmenopausal Women: Limitations of BMI as a Predictor of Sarcopenic Obesity

AGING MEDICINE, EarlyView.
The prevalence of sarcopenia and sarcopenic obesity is large among community‐dwelling postmenopausal women, and lower body mass index is a significant predictor of both. The finding that low body mass index predicts both sarcopenia and sarcopenic obesity, highlights the limitation of body mass index as a measure of adiposity in the assessment of ...
Remya Rajan, Kripa Cherian, Thomas Paul, Hesarghatta Shyamasunder Asha, Arun Jose, Grace Rebekah, Nihal Thomas, Nitin Kapoor   +7 more
wiley   +1 more source

SLPI is a critical mediator that controls PTH-induced bone formation

Nature Communications, 2021
The mechanism by which parathyroid hormone mediates the switch from bone resorption to bone formation is unclear. Here, the authors show that SLPI regulates the communication between osteoblasts and osteoclasts to promote the anabolic effect of ...
Akito Morimoto, Junichi Kikuta, Keizo Nishikawa, Takao Sudo, Maki Uenaka, Masayuki Furuya, Tetsuo Hasegawa, Kunihiko Hashimoto, Hiroyuki Tsukazaki, Shigeto Seno, Akira Nakamura, Daisuke Okuzaki, Fuminori Sugihara, Akinori Ninomiya, Takeshi Yoshimura, Ryoko Takao-Kawabata, Hideo Matsuda, Masaru Ishii   +17 more
doaj   +1 more source