Results 41 to 50 of about 120,496 (233)

Effect of eplerenone on parathyroid hormone levels in patients with primary hyperparathyroidism: a randomized, double-blind, placebo-controlled trial [PDF]

, 2012
Background Increasing evidence suggests the bidirectional interplay between parathyroid hormone and aldosterone as an important mechanism behind the increased risk of cardiovascular damage and bone disease observed in primary hyperparathyroidism.
A Struthers, A Tomaschitz, A Tomaschitz, A Tomaschitz, A Tomaschitz, A Tomaschitz, AA Zia, Albrecht Schmidt, Andreas Meinitzer, Andreas Tomaschitz, AS Mihailidou, Astrid Fahrleitner-Pammer, B Pitt, Burkert Pieske, C Letizia, C Maniero, CA Feldstein, Caterina Colantonio, CG Ogard, CS Fox, DA Sica, E Hagstrom, E Rodriguez-Ayala, Eberhard Ritz, Elisabeth Kraigher-Krainer, F Edelmann, FP Cappuccio, G Mazzocchi, HN Hulter, IL Nilsson, J Lemann Jr, J Rosenberg, JJ McMurray, JM Moseley, JN Cooper, JP Bilezikian, Jörg H Horina, K Amrein, K Olgaard, Karin Amrein, Katharina Kienreich, L Brunaud, L Kovacs, L Morfis, LD Carbone, MH Weinberger, MR Rubin, Nicolas Verheyen, PH Law, R Eastell, R Pacifici, RA Wermers, S Pilz, S Pilz, S Pilz, S Pilz, S van Diepen, SJ Silverberg, Stefan Pilz, T Koal, VS Chhokar, YM Yoo   +61 more
core   +3 more sources

A head start: The relationship of placental factors to craniofacial and brain development

Developmental Dynamics, EarlyView.
Abstract In recent years, the importance of placental function for fetal neurodevelopment has become increasingly studied. This field, known as neuroplacentology, has greatly expanded possible etiologies of neurodevelopmental disorders by exploring the influence of placental function on brain development.
Annemarie Jenna Carver, Martine Dunnwald, Hanna Elizabeth Stevens   +2 more
wiley   +1 more source

Gαq signalling from endosomes: A new conundrum

British Journal of Pharmacology, EarlyView., 2023
Abstract G‐protein‐coupled receptors (GPCRs) constitute the largest family of membrane receptors, and are involved in the transmission of a variety of extracellular stimuli such as hormones, neurotransmitters, light and odorants into intracellular responses.
Carole Daly, Bianca Plouffe
wiley   +1 more source

Bisphosphonate's and Intermittent Parathyroid Hormone's Effect on Human Spinal Fusion: A Systematic Review of the Literature. [PDF]

, 2017
There has been a conscious effort to address osteoporosis in the aging population. As bisphosphonate and intermittent parathyroid hormone (PTH) therapy become more widely prescribed to treat osteoporosis, it is important to understand their effects on ...
Acosta, Frank L, Hah, Raymond, Hsieh, Patrick C, Iorio, Justin A, Jakoi, Andre M, Liu, John C, Patel, Neil N, Pham, Martin H, Stone, Michael A, Wang, Jeffrey C   +9 more
core   +2 more sources

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Retinal micro-vascular and aortic macro-vascular changes in postmenopausal women with primary hyperparathyroidism [PDF]

, 2018
Aim of the study was to evaluate the micro and macro-vascular changes in patients with primary hyperparathyroidism (PHPT) compared to controls. 30 postmenopausal PHPT women (15 hypertensive and 15 normotensive) and 30 normotensive controls underwent ...
Biamonte, Federica, Cipriani, Cristiana, Colangelo, Luciano, Curione, Mario, Minisola, Salvatore, Parravano, Mariacristina, Pepe, Jessica, Tedeschi, Massimiliano, Varano, Monica   +8 more
core   +2 more sources

Effects of perampanel on bone health in adult patients with epilepsy

Epilepsia Open, EarlyView.
Abstract Objective The objective was to assess the effects of perampanel (PER) on bone metabolism and bone mineral density (BMD) in adult patients with epilepsy. Methods This retrospective study included consecutive patients admitted to the Epilepsy Center of Sichuan Provincial People's Hospital from January 2023 to June 2024.
Mingxing Yu, Nana Zhang, Chunyan Chen, Yuxuan He, Jing Meng, Wen Luo, Yi Liang, Yi Guo, Liang Yu   +8 more
wiley   +1 more source

Impaired Insulin sensitivity and Insulin secretion in Haemodialysis patients with and without Secondary Hyperparathyroidism [PDF]

, 2004
The aim of our study was to investigate insulin sensitivity and beta cell function in hemodialysis (HD) patients without diabetes. We hypothesized that parathyroid gland function was a determinant of insulin sensitivity and/or beta cell function.
Gluvic, Zoran M., Komadina, Ljiljana, Milic, Natasa, Perunicic-Pekovic, Gordana, Pljesa, Steva, Rasic-Milutinovic, Zorica   +5 more
core  

Loss of Nmp4 optimizes osteogenic metabolism and secretion to enhance bone quality [PDF]

, 2019
A goal of osteoporosis therapy is to restore lost bone with structurally sound tissue. Mice lacking the transcription factor Nuclear Matrix Protein 4 (Nmp4, Zfp384, Ciz, ZNF384) respond to several classes of osteoporosis drugs with enhanced bone ...
Adaway, Michele, Allen, Matthew R., Bidwell, Joseph P., Brustovetsky, Nickolay, Burr, David B., Childress, Paul J., Hamilton, James, Jacobs, Kylie, Klunk, Angela, Liu, Yunlong, Misra, Jagannath, Mosley, Amber L., Robling, Alexander G., Shao, Yu, Stayrook, Keith R., Vashishth, Deepak, Wallace, Joseph M., Wek, Ronald C., Wichern, Emily   +18 more
core   +1 more source

Prognosis and Phenotypes of Advanced Head and Neck Carcinoma Associated With Hypercalcemia

Head &Neck, EarlyView.
ABSTRACT Purpose Hypercalcemia is the most common metabolic disorder in cancer, affecting 10%–20% of patients with advanced malignancies, including squamous cell carcinoma of the head and neck (HNSCC), though its prognostic significance remains poorly studied.
Elodie Mamou, Paul Gougis, Baptiste Abbar, Jean‐philippe Spano, Laetitia Morardet, Aurore Vozy   +5 more
wiley   +1 more source