Results 51 to 60 of about 146,694 (331)
Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives
Advanced Science, EarlyView.Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu +13 more
wiley +1 more source
Advanced Science, EarlyView.This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao +17 more
wiley +1 more source
BMC Veterinary Research, 2020 Background Vitamin D deficiency and related metabolic bone diseases in pet rabbits have been intermittently debated. In human research, the parathyroid hormone concentration in relation to the 25-hydroxyvitamin D concentration is used to determine ...
J. Mäkitaipale +3 more
doaj +1 more source
Parathyroid hormone-related peptide stimulates intestinal strontium absorption in Camels (Camelus dromedarius) [PDF]
, 2008 The present work was undertaken to evaluate the stimulatory effect of Parathyroid hormone-related peptide (PTHrP) on the intestinal calcium (Ca) absorption using stable strontium (Sr) as a surgoate marker in 10 Camels.
Coxam, Véronique +7 more
core
Positioning novel biologicals in CKD-mineral and bone disorders [PDF]
, 2017 Renal osteodystrophy (ROD), the histologic bone lesions of chronic kidney disease (CKD), is now included in a wider syndrome with laboratory abnormalities of mineral metabolism and extra-skeletal calcifications or CKD-mineral and bone disorders (CKD-MBD),
Covic, Adrian +5 more
core +1 more source
Post‐Translational Modifications in Cilia and Ciliopathies
Advanced Science, EarlyView.This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley +1 more source
Advanced Science, EarlyView.Obese gut‐microbiota derived lipopolysaccharides (LPS) induce bone marrow macrophage senescence and GCA secretion via activating TLR4/NF‐κB/MAPKs pathway. Clinically, obese patients are associated with higher serum GCA levels. Mice with depletion of GCA gene show resistance to skeletal deterioration caused by obesity and LPS‐induced chronic ...
Min Huang +16 more
wiley +1 more source
Kidney International Reports, 2019 Introduction: Calcimimetics improve parameters of secondary hyperparathyroidism (sHPT) but are mostly initiated when patients have severe disease, potentially limiting effectiveness.
John Cunningham +8 more
doaj
Functioning lipoadenoma of parathyroid gland [PDF]
Scripta Medica, 2012 We are describing a case of primary hyperparatyroidism due to lipoadenoma of the parathyroid gland. After removal of the lipoadenoma, intraoperatively, there was an immediate decrease in the parathyroid hormone level.
Okleh Akram, Czapar Carol, Sekosan Marin
doaj
Estimated glomerular filtration rate is a poor predictor of the concentration of middle molecular weight uremic solutes in chronic kidney disease [PDF]
, 2012 Background: Uremic solute concentration increases as Glomerular Filtration Rate (GFR) declines. Weak associations were demonstrated between estimated GFR (eGFR) and the concentrations of several small water-soluble and protein-bound uremic solutes ...
Barreto, Daniela V +9 more
core +5 more sources