Results 61 to 70 of about 1,155,277 (353)

24R,25(OH)2D3 regulates tumorigenesis in estrogen sensitive laryngeal cancer cells via membrane‐associated receptor complexes in ER+ and ER− cells

International Journal of Cancer, EarlyView.
What's New? Estrogen receptors likely influence the development of laryngeal cancer and are of particular interest in regard to their relationship with the vitamin D metabolite 24R,25(OH)2D3. In this study the authors examined interactions between 24R,25(OH)2D3 and estrogen‐responsive laryngeal tumorigenesis.
Cydney D. Dennis, D. Joshua Cohen, Kusal Debnath, Nofrat Schwartz, Brock P. Lodato, Jonathan T. Dillon, Tillat Batool, Matthew S. Halquist, Preetam Ghosh, Zvi Schwartz, Barbara D. Boyan   +10 more
wiley   +1 more source

An Evaluation of Oral Subchronic Toxicity of Maizinol (UP165), a Zea mays Leaf Extract

Journal of Applied Toxicology, EarlyView.
ABSTRACT Maize (Zea mays) has been consumed by humans for millennia and represents the third most abundant crop grown globally. Maize and maize‐derived products have a long history of safe consumption from bread and other cereal products in human diets worldwide. Aside from key dietary components like carbohydrates and proteins, the corn plant contains
J. Kyle Weston, Barry S. Lynch, James A. Akingbasote   +2 more
wiley   +1 more source

PARATHYROID HORMONE-RELATED PROTEIN AND PROSTATE CANCER

Кубанский научный медицинский вестник, 2017
The survey presents the existing arguments and facts about the parathyroid hormone-related protein (PTHrP) and its role in pathophysiological and pathobio-chemical mechanisms that are related to onco-transformation of prostate.
V. L. MEDVEDEV, E. A. STRYGINA, A. N. KURZANOV   +2 more
doaj   +1 more source

Biosynthesis of Proparathyroid Hormone and Parathyroid Hormone by Human Parathyroid Glands [PDF]

Journal of Clinical Investigation, 1973
Human parathyroid glands obtained at autopsy were incubated with [(3)H]leucine and [(3)H]lysine. After incubation, nonradioactive parathyroid tissue of either human or bovine origin was added. Radioactive parathyroid hormone and proparathyroid hormone were isolated from the gland and medium by organic solvent and salt fractionation, trichloroacetic ...
David V. Cohn, James W. Hamilton, Paul I. Liu, Luke L. H. Chu, Ronal R. Macgregor   +4 more
openaire   +3 more sources

Case Report and Literature Review: Intrathyroid Thymic Carcinoma

Journal of Clinical Ultrasound, EarlyView.
This case report highlights the challenges in diagnosing intrathyroid thymic carcinoma (ITTC), a rare thyroid tumor, and underscores the importance of postoperative pathology for confirmation. The study emphasizes the good prognosis of ITTC with appropriate surgical management.
Jia‐Yue Sun, Ji Qi, Yi‐Lin Hou, Yun‐Fei Zhang   +3 more
wiley   +1 more source

Cardiovascular actions of parathyroid hormone and parathyroid hormone-related peptide [PDF]

Cardiovascular Research, 1998
Cardiovascular cells (cardiomyocytes and smooth muscle cells) are target cells for parathyroid hormone (PTH) and the structurally related peptide parathyroid hormone-related peptide (PTH-rP). PTH activates protein kinase C (PKC) of cardiomyocytes via a PKC activating domain previously identified on chondrocytes.
Klaus-Dieter Schlüter, Hans Michael Piper   +1 more
openaire   +3 more sources

Impact of Denosumab Adherence on Renal Function and Mortality Rates in Type 2 Diabetes Patients With Osteoporosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Type 2 diabetes mellitus (T2DM) is associated with an increased risk of osteoporosis and fractures, and denosumab, a non‐kidney‐excreted antiresorptive medication, represents a viable alternative to bisphosphonates for osteoporosis treatment in patients with T2DM. This study aimed to investigate the association among denosumab adherence, renal
Yu‐Chuan Chang, Jian‐Chih Chen, Sung‐Yen Lin, Kun‐Der Lin, Pei‐Shan Ho, Chung‐Hwan Chen, Yin‐Chih Fu, Tien‐Ching Lee   +7 more
wiley   +1 more source

Biomedical Applications of 3D‐Printed Polyamide: A Systematic Review

Macromolecular Materials and Engineering, EarlyView.
Additive manufacturing expands possibilities for personalized biomedical solutions, emphasizing the role of material science. This review examines the mechanical properties of 3D printed polyamide and explores its advantages and limitations in biomedical applications, including personalized implants, medical devices, and patient‐specific tools, as well,
Emese Paari‐Molnar, Wa'el Nafith Abdel‐Fattah Qa'dan, Kinga Kardos, Roland Told, Nitin Sahai, Peter Varga, Szilard Rendeki, Gabor Szabo, Kata Fekete, Tihamer Molnar, Adam Tibor Schlegl, Peter Maroti, Luca Toth   +12 more
wiley   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

RRP12 Variants Are Associated With Autosomal Recessive Brain Calcifications

Movement Disorders, EarlyView.
Abstract Background Primary brain calcifications are observed in several inherited diseases due to different pathogenic mechanisms, including the disruption of the neurovascular unit, mitochondrial dysfunction, and impaired nucleic acid metabolism.
Edoardo Monfrini, Paola Rinchetti, Mathieu Anheim, Anna Klingseisen, Ouhaid Lagha‐Boukbiza, Zhidong Cen, Dehao Yang, Xinhui Chen, Reza Maroofian, Henry Houlden, Gioia Cappelletti, Anne‐Claire Richard, Olivier Quenez, Camilo Toro, Steven J. Frucht, Francesco Lotti, Wei Luo, David Hunt, Gael Nicolas, Giulietta M. Riboldi   +19 more
wiley   +1 more source