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Molecular Mechanisms of Parathyroid Disorders in Chronic Kidney Disease
Secondary hyperparathyroidism (SHP) is a common complication of chronic kidney disease (CKD) that induces morbidity and mortality in patients. How CKD stimulates the parathyroid to increase parathyroid hormone (PTH) secretion, gene expression and cell ...
Alia Hassan +6 more
doaj +1 more source
Parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP) are two peptides that regulate mineral ion homeostasis, skeletal development, and bone turnover by activating parathyroid hormone 1 receptor (PTH1R). PTH1R signaling is of profound
Ping Lyu +7 more
doaj +1 more source
European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism
Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz +3 more
wiley +1 more source
Thymus-associated parathyroid hormone has two cellular origins with distinct endocrine and immunological functions. [PDF]
In mammals, parathyroid hormone (PTH) is a key regulator of extracellular calcium and inorganic phosphorus homeostasis. Although the parathyroid glands were thought to be the only source of PTH, extra-parathyroid PTH production in the thymus, which ...
Zhijie Liu +6 more
doaj +1 more source
Parathyroid hormone receptors in GtoPdb v.2021.3
The parathyroid hormone receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Parathyroid Hormone Receptors [49]) are class B G protein-coupled receptors.
Jueppner, H +11 more
core +1 more source
A rare case of ectopic parathyroid cyst associated with Hashimoto thyroiditis
Introduction: Parathyroid cyst is a rare parathyroid disorder and represented
Claudia Alexandrina Irimie +3 more
doaj +1 more source
Parathyroid glands contain the vitamin D receptor (VDR) and 25-hydroxyvitamin D-1α-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24A1), which catalyze the production and degradation of 1,25-dihydroxyvitamin D [1,25(OH)2D], respectively.
Yi Jiang +4 more
doaj +1 more source
Origin of parathyroid hormone (PTH) fragments detected by intact-PTH assays [PDF]
BACKGROUND: Intact parathyroid hormone (I-PTH) assays react with non-(1-84)PTH, large carboxyl-terminal (C) fragments with a partially preserved amino-terminal (N) structure. They account for up to 50% of I-PTH in renal failure and may be implicated in PTH resistance.
L, Nguyen-Yamamoto +6 more
openaire +2 more sources
Parathyroid hormone (PTH), PTH-derived peptides, and new PTH assays in renal osteodystrophy [PDF]
Parathyroid hormone (PTH), PTH-derived peptides, and new PTH assays in renal osteodystrophy. Reliable measurements of parathyroid hormone (PTH) concentrations in serum or plasma are critical for the appropriate diagnosis and management of patients with renal osteodystrophy.
Goodman, William G. +3 more
openaire +2 more sources
Parathyroid hormone as early marker of derangements of mineral metabolism among patients in various stages of chronic kidney disease [PDF]
Background: Chronic Kidney Disease (CKD) is an international public health problem affecting about 5-10% of the population. As kidney function declines, there is a progressive deterioration in mineral homeostasis with disruption of normal serum ...
M. Rasheed Khan +3 more
doaj

